Evidence map›Paper›PMID 41589928›Full record

ArticleBiomimetics (Basel, Switzerland)2025

Towards Biomimetic Robotic Rehabilitation: Pilot Study of an Upper-Limb Cable-Driven Exoskeleton in Post-Stroke Patients.

Develyn I S Bastos, Sergio C M Gomes, Eduardo A F Dias, Pedro H F Ulhoa, Raphaele C J S Gomes, Fabiana D Marinho, Rafhael M Andrade

Abstract read
In one paragraph

Article in Biomimetics (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Develyn I S BastosPostgraduate Postgraduate Program in Biotechnology, Universidade Federal do Espirito Santo, R. Dióscoro Carneiro Filho, 1-27, Vitória 29047-009, ES, Brazil.
Sergio C M GomesPostgraduate Postgraduate Program in Biotechnology, Universidade Federal do Espirito Santo, R. Dióscoro Carneiro Filho, 1-27, Vitória 29047-009, ES, Brazil.
Eduardo A F DiasPostgraduate Program in Mechanical Engineering, Universidade Federal do Espirito Santo, Av. Fernando Ferrari, 514, Vitória 29075-910, ES, Brazil.
Pedro H F UlhoaPostgraduate Program in Electrical Engineering, Universidade Federal do Espirito Santo, Av. Fernando Ferrari, 514, Vitória 29075-910, ES, Brazil.ORCID 0000-0003-1164-8518
Raphaele C J S GomesPostgraduate Postgraduate Program in Biotechnology, Universidade Federal do Espirito Santo, R. Dióscoro Carneiro Filho, 1-27, Vitória 29047-009, ES, Brazil.
Fabiana D MarinhoDepartment of Occupational Therapy, Universidade Federal do Espirito Santo, R. Dióscoro Carneiro Filho, 1-27, Vitória 29047-009, ES, Brazil.
Rafhael M AndradePostgraduate Postgraduate Program in Biotechnology, Universidade Federal do Espirito Santo, R. Dióscoro Carneiro Filho, 1-27, Vitória 29047-009, ES, Brazil.ORCID 0000-0002-2839-3649

Funding

Brazilian National Council for Scientific and Technological Development project 402317/2023-8, project 305367/2024-2, and project 408420/2024-3Fundação de Amparo à Pesquisa e Inovação do Espírito Santo TO: 946/2023, No. 2023-F0GWQ)
6 · The paper itself

Abstract

Stroke is a leading cause of disability, often resulting in motor, cognitive, and language deficits, with significant impact on upper-limb function. Robotic therapy (RT) has emerged as an effective strategy, providing intensive, repetitive, and adaptable practice to optimize functional recovery. This pilot study aimed to describe and evaluate the effects of robotic rehabilitation as a complement to conventional therapy, using a biomimetic activities-of-daily-living (ADL)-based protocol, on upper-limb function in post-stroke patients. Three participants (aged 30-80 years) undergoing occupational and/or physiotherapy received individualized robotic training with a lightweight cable-driven upper-limb exoskeleton, m-FLEX™, twice a week for ten weeks (30 min per session). Movements were designed to mimic natural upper-limb actions, including elbow flexion-extension, forearm pronation-supination, tripod pinch, and functional tasks such as grasping a cup. Assessments included the Fugl-Meyer (FM) scale, the Functional Independence Measure (FIM), and device satisfaction, performed at baseline, mid-intervention, and post-intervention. Descriptive analysis of the tabulated data revealed improvements in range of motion and functional outcomes. These findings suggest that biomimetic protocol of robotic rehabilitation, when combined with conventional therapy, can enhance motor and functional recovery in post-stroke patients.

Indexed as

neuromotor rehabilitationstrokeupper-limb exoskeleton

Identifiers

PMID41589928
PMCPMC12839029

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.