Evidence map›Paper›PMID 41589749›Full record

ArticleJournal of lower genital tract disease2026

Higher Diagnostic Accuracy of an AI Model for Colposcopy Compared With Conventional and Digital Colposcopic Evaluation.

Berit B Booth, Smith K Khare, Victoria Blanes-Vidal, Pinar Bor, Esmaeil S Nadimi, Lone K Petersen

Abstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of lower genital tract disease, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. [An auxiliary diagnosis system for cervical intraepithelial neoplasia based on colposcopic images].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Berit B BoothDepartment of Gynecology and Obstetrics, Odense University Hospital, Odense.ORCID 0000-0002-9134-804
Smith K KhareApplied AI and Data Science Unit, Mærsk Mc-Kinney Møller Institute, Faculty of Engineering, University of Southern Denmark.
Victoria Blanes-VidalApplied AI and Data Science Unit, Mærsk Mc-Kinney Møller Institute, Faculty of Engineering, University of Southern Denmark.
Pinar BorDepartment of Gynecology and Obstetrics, Aarhus University Hospital, Aarhus.
Esmaeil S NadimiApplied AI and Data Science Unit, Mærsk Mc-Kinney Møller Institute, Faculty of Engineering, University of Southern Denmark.
Lone K PetersenDepartment of Gynecology and Obstetrics, Odense University Hospital, Odense.

Funding

Beta Health Foundation 2023-1384
6 · The paper itself

Abstract

objectiveColposcopy involves subjective visual assessment of cervical features that may indicate cervical dysplasia. Pattern recognition during colposcopy could be enhanced by artificial intelligence (AI). Using colposcopy images with precisely mapped multiple biopsy sites and corresponding histologic diagnoses, we developed an AI model, Cervix-AID-Net, to classify colposcopy images into low-grade disease [less than cervical intraepithelial neoplasia (CIN) grade 2] and high-grade disease (CIN grade 2 or above). The objective of this study was to compare the diagnostic performance of the Cervix-AID-Net model with the digital colposcope (DySIS) color map and colposcopists' interpretations of the cervix in identifying low-grade and high-grade disease.

methodsThe authors used 3,153 colposcopy images from 178 women, each with 4 biopsies, to train and validate the algorithm. Sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were calculated with 95% CIs.

resultsCervix-AID-Net achieved a diagnostic accuracy of 99.8% (95% CI: 99.6-99.9) in classifying colposcopy images into low-grade and high-grade categories. This was significantly higher than the DySIS color map accuracy of 58.8% (95% CI: 51.1-66.1) and the accuracy of the colposcopist's visual impression of the cervix (55.1%, 95% CI: 47.2%-62.5%).

conclusionThis first version of the Cervix-AID-Net demonstrated superior diagnostic accuracy compared with both the DySIS color map and colposcopists' visual assessment. The results need confirmation in a prospective clinical trial.

Indexed as

Artificial IntelligenceColposcopyUterine Cervical DysplasiaUterine Cervical NeoplasmsAdultAgedFemaleHumansMiddle AgedSensitivity and SpecificityYoung Adultartificial intelligencecervical cancercervical dysplasiacervical intraepithelial neoplasiacolposcopy

Identifiers

PMID41589749
PMCPMC12994893

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.