Evidence map›Paper›PMID 41589562›Full record

ArticleEuropean journal of pain (London, England)2026

The para

Serena Mares Malta, Lucas Ian Veloso Correia, Alexandre Souza Marquez, Lucas Matos Martins Bernardes, John George Howland, Ana Paula Mendes-Silva, Foued Salmen Espíndola, Carlos Ueira-Vieira

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of pain (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The paraEuropean journal of pain (London, England) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Serena Mares MaltaLaboratory of Genetics, Institute of Biotechnology, Federal University of Uberlandia, Uberlandia, Minas Gerais, Brazil.ORCID https://orcid.org/0000-0002-9330-9503
Lucas Ian Veloso CorreiaLaboratory of Nanobiotechnology, Institute of Biotechnology, Federal University of Uberlandia, Uberlandia, Minas Gerais, Brazil.
Alexandre Souza MarquezLaboratory of Genetics, Institute of Biotechnology, Federal University of Uberlandia, Uberlandia, Minas Gerais, Brazil.
Lucas Matos Martins BernardesLaboratory of Genetics, Institute of Biotechnology, Federal University of Uberlandia, Uberlandia, Minas Gerais, Brazil.ORCID https://orcid.org/0009-0003-9250-5996
John George HowlandDepartment of Anatomy, Physiology and Pharmacology, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID https://orcid.org/0000-0003-3326-7118
Ana Paula Mendes-SilvaDepartment of Psychiatry, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID https://orcid.org/0000-0002-0636-7239
Foued Salmen EspíndolaLaboratory of Biochemistry and Molecular Biology, Institute of Biotechnology, Federal University of Uberlândia, Uberlandia, Minas Gerais, Brazil.ORCID https://orcid.org/0000-0002-6937-1411
Carlos Ueira-VieiraLaboratory of Genetics, Institute of Biotechnology, Federal University of Uberlandia, Uberlandia, Minas Gerais, Brazil.

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
CAPES (Coordenação de Aperfeiçoamento de Pessoal de Nível Superior)FAPEMIG (Fundação de Amparo à Pesquisa do Estado de Minas Gerais)NIH HHS P40 OD018537
6 · The paper itself

Abstract

backgroundChronic pain, which is often unrelated to ongoing injury, is poorly understood and difficult to treat. Genetic studies have identified voltage-gated sodium (Na

methodsA chronic pain model was proposed in Drosophila using the para

resultsSequence alignment and 3D structural modelling revealed strong homology between human Na

conclusionsThe para SIGNIFICANCE STATEMENT: This study proposes the Drosophila melanogaster para

Indexed as

AnalgesicsCannabidiolChronic PainDrosophila ProteinsNociceptionAnimalsCarbamazepineDisease Models, AnimalDrosophila melanogasterNAV1.7 Voltage-Gated Sodium ChannelSodium ChannelsAnalgesicsCannabidiolCarbamazepineDrosophila ProteinsNAV1.7 Voltage-Gated Sodium Channelpara protein, DrosophilaSodium Channelscannabidiolchronic pain modelDrosophila melanogasternociceptionparabss1 mutant

Identifiers

PMID41589562
PMCPMC12836457

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.