Evidence map›Paper›PMID 41589453›Full record

SynthesisJournal of pediatric gastroenterology and nutrition2026

Risk factors for avoidant/restrictive food intake disorder in children: A systematic review.

Relana Nowacki, Lisanne Arayess, Jos Kleijnen, Anita Vreugdenhil, Sandra Mulkens

Abstract readSystematic Review
In one paragraph

Synthesis in Journal of pediatric gastroenterology and nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Relana NowackiMosaKids Children's Hospital, Maastricht University Medical Center (MUMC+), Maastricht University, Maastricht, The Netherlands.ORCID https://orcid.org/0009-0002-1979-0228
Lisanne ArayessMosaKids Children's Hospital, Maastricht University Medical Center (MUMC+), Maastricht University, Maastricht, The Netherlands.
Jos KleijnenKleijnen Systematic Reviews Limited, York, England.
Anita VreugdenhilMosaKids Children's Hospital, Maastricht University Medical Center (MUMC+), Maastricht University, Maastricht, The Netherlands.
Sandra MulkensDepartment of Research and Development, SeysCentra, Malden, The Netherlands.

Funding

None
6 · The paper itself

Abstract

objectivesAvoidant/restrictive food intake disorder (ARFID) is a relatively new diagnosis in the Diagnostic and Statistical Manual of Mental Disorders (DSM)-5, since 2013. The restrictive and/or selective eating-driven by a lack of interest, sensory sensitivity, and/or concern over aversive consequences-is associated with significant medical and/or psychosocial problems. However, little is known about risk factors of this feeding/eating disorder. Our objective was to investigate which factors predispose to ARFID in children.

methodsDatabases CINAHL, Embase, PsycINFO, PubMed, and Web of Science were searched to identify peer-reviewed articles published from inception to August 27, 2024. Articles that included children with ARFID, a control group, and a potential risk factor were selected.

resultsA total of six studies were included in this review. In these studies, data regarding potential risk factors and their risk of bias were evaluated. All studies were of cross-sectional design. Despite an extensive search strategy, only a small number of studies could be included for analysis. A total of 18 factors were reported, of which 10 factors were significantly associated with ARFID. These factors include physical factors, psychiatric comorbidities, and maternal psychopathological risk.

conclusionsThis systematic review shows which factors are associated with ARFID in children. To better clarify the direction of associations between potential risk factors and ARFID, longitudinal and interventional studies are needed. This knowledge may support early recognition and timely intervention in ARFID.

Indexed as

Avoidant Restrictive Food Intake DisorderFeeding and Eating DisordersChildFemaleHumansRisk Factorsfeeding and eating disordersfood selectivitypsychiatric comorbidity

Identifiers

PMID41589453
PMCPMC13050801

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.