Evidence map›Paper›PMID 41589237›Full record

ArticleInternational cancer conference journal2026

Rectal adenocarcinoma with a yolk sac tumor component: A rare case report and review of the literature.

Sato Nishida, Tomohiro Takeda, Tatsuya Shonaka, Shoichiro Mizukami, Masahide Otani, Mizuho Ohara, Chikayoshi Tani, Kimiharu Hasegawa, Yuki Kamikokura, Mishie Tanino and 1 more

Abstract read
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Article in International cancer conference journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Sato NishidaDivision of Gastrointestinal Surgery, Department of Surgery, Asahikawa Medical University, 2-1 Midorigaoka Higashi, Asahikawa, 078-8510 Hokkaido Japan.ORCID 0009-0007-7263-2022
Tomohiro TakedaDivision of Gastrointestinal Surgery, Department of Surgery, Asahikawa Medical University, 2-1 Midorigaoka Higashi, Asahikawa, 078-8510 Hokkaido Japan.ORCID 0000-0003-4820-8532
Tatsuya ShonakaDivision of Gastrointestinal Surgery, Department of Surgery, Asahikawa Medical University, 2-1 Midorigaoka Higashi, Asahikawa, 078-8510 Hokkaido Japan.
Shoichiro MizukamiDivision of Gastrointestinal Surgery, Department of Surgery, Asahikawa Medical University, 2-1 Midorigaoka Higashi, Asahikawa, 078-8510 Hokkaido Japan.
Masahide OtaniDivision of Gastrointestinal Surgery, Department of Surgery, Asahikawa Medical University, 2-1 Midorigaoka Higashi, Asahikawa, 078-8510 Hokkaido Japan.
Mizuho OharaDivision of Gastrointestinal Surgery, Department of Surgery, Asahikawa Medical University, 2-1 Midorigaoka Higashi, Asahikawa, 078-8510 Hokkaido Japan.
Chikayoshi TaniDivision of Gastrointestinal Surgery, Department of Surgery, Asahikawa Medical University, 2-1 Midorigaoka Higashi, Asahikawa, 078-8510 Hokkaido Japan.
Kimiharu HasegawaDivision of Gastrointestinal Surgery, Department of Surgery, Asahikawa Medical University, 2-1 Midorigaoka Higashi, Asahikawa, 078-8510 Hokkaido Japan.
Yuki KamikokuraDepartment of Diagnostic Pathology, Asahikawa Medical University Hospital, Asahikawa, Hokkaido Japan.
Mishie TaninoDepartment of Diagnostic Pathology, Asahikawa Medical University Hospital, Asahikawa, Hokkaido Japan.
Hideki YokooDivision of Hepatobiliary Pancreatic and Transplantation Surgery, Department of Surgery, Asahikawa Medical University, Asahikawa, Hokkaido Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Yolk sac tumor (YST) occurs primarily in the gonads but rarely outside the gonads. They typically arise in the midline location, and there are only a few reports describing the colon and rectum as the primary sites of YST. Additionally, colorectal cancers containing YST-like components are rare, and in other organs, including the stomach, it is more common to describe such lesions as " yolk sac tumor-like carcinoma". Here, we report a case of colorectal adenocarcinoma with a YST-like component arising in the rectum. This is the seventh reported case of colorectal YST-like carcinoma. A 66-year-old man presented to our hospital with the chief complaint of anal bleeding. Colonoscopy revealed a 25 × 20 mm tumor located 5 cm above the anal verge. Biopsy results showed moderately differentiated tubular adenocarcinoma, cT3, cN2b, cM0, and cStage IIIC (UICC 8th edition). Subsequently, a laparoscopic abdominoperineal resection was performed. A histopathological examination of the resected specimen revealed findings of adenocarcinoma and YST-like component. Immunostaining for mismatch repair proteins revealed no abnormalities. The tumor was positive for the

Indexed as

Extragonadal germ cell tumorRectal adenocarcinomaYolk sac tumor

Identifiers

PMID41589237
PMCPMC12831757

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.