Evidence map›Paper›PMID 41589177›Full record

ArticleCureus2025

Three-Dimensional Laparoscopic Varicocelectomy as the New Microsurgical Technique: Safety, Efficiency, and Outcomes.

Filippos Nikitakis, Nikolaos Grivas, Christos Zabaftis, Maria Chalkidou, Athanasios Bouchalakis, Smaragda Tsela, Markos Karavitakis

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Filippos Nikitakis2nd Department of Urology, Lefkos Stavros - The Athens Clinic, Athens, GRC.
Nikolaos Grivas2nd Department of Urology, Lefkos Stavros - The Athens Clinic, Athens, GRC.
Christos Zabaftis2nd Department of Urology, Lefkos Stavros - The Athens Clinic, Athens, GRC.
Maria Chalkidou2nd Department of Urology, Lefkos Stavros - The Athens Clinic, Athens, GRC.
Athanasios Bouchalakis2nd Department of Urology, Lefkos Stavros - The Athens Clinic, Athens, GRC.
Smaragda Tsela2nd Department of Urology, Lefkos Stavros - The Athens Clinic, Athens, GRC.
Markos Karavitakis2nd Department of Urology, Lefkos Stavros - The Athens Clinic, Athens, GRC.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Varicocele is a prevalent and potentially correctable cause of male infertility. Surgical intervention is recommended in men with varicocele and abnormal semen parameters. Although three-dimensional (3D) laparoscopy has been widely adopted in urologic surgery, its role in varicocelectomy remains insufficiently investigated. Objectives The aim of this study was to evaluate the safety, efficiency, and outcomes of 3D laparoscopic varicocelectomy in a cohort of patients with ultrasound-confirmed varicocele, and to explore whether this approach can serve as a valid alternative to microsurgical varicocelectomy. Materials and methods We retrospectively analyzed 34 consecutive patients who underwent 3D laparoscopic varicocelectomy using a standardized approach emphasizing precise anatomical dissection. No adjunctive Doppler or vital dyes were used. Key outcomes included operative time, intraoperative and postoperative complications, recurrence rate, pain scores, patient satisfaction, and semen parameters at six months. Results The mean operative time was 22.3 minutes, significantly shorter than reported averages in conventional laparoscopic or microsurgical series. No intraoperative or postoperative complications were recorded, including hydrocele (0%) or testicular atrophy (0%). There was one (1.85%) case of recurrence of varicocele. Postoperative pain was minimal, with a mean visual analog scale (VAS) score of 1.2/10 at 24 hours, and no patients required opioids beyond the first postoperative day. Overall, patient satisfaction was high: 94.1% rated their experience as "very good" or "excellent" at the six-week follow-up. Semen parameters improved significantly: mean sperm concentration increased from 15.1 ×10⁶/mL to 34.3 ×10⁶/mL, and progressive motility from 28.4% to 44.9% (p < 0.01). Conclusion Three-dimensional laparoscopic varicocelectomy demonstrates excellent safety, minimal discomfort, high patient satisfaction, and strong functional outcomes. With the advantages of shorter operative time and a low complication rate, it may represent a viable modern alternative to microsurgical varicocelectomy in expert centres.

Indexed as

laparoscopic varicocelectomymale infertilityminimally invasive surgerythree-dimensional laparoscopyvaricocele treatment

Identifiers

PMID41589177
PMCPMC12832150

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