ArticleCureus2025
A Fulminant Case of Incontinentia Pigmenti Presenting With Early Neuro-Ophthalmologic Manifestations.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
Incontinentia pigmenti (IP) is a rare, X-linked dominant, multisystemic genetic disorder. We report the case of a female neonate presenting with vesiculobullous and erythematous cutaneous lesions involving the hands and feet. Concurrently, she exhibited repetitive flexion movements of all four limbs, which rapidly progressed to status epilepticus. The clinical course was rapidly unfavorable, marked by diffuse retinal ischemia and cerebral palsy. This patient's clinical history illustrates the potential severity of the neurological and ophthalmologic manifestations of IP. It underscores the need to consider IP in the differential diagnosis of cutaneous lesions associated with neurological symptoms in female infants. Early recognition is essential to ensure close monitoring and initiate appropriate multidisciplinary management.
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