Evidence map›Paper›PMID 41589169›Full record

ArticleCureus2025

Combined Heart-Liver Transplantation: A First Successful Case in Chile.

Cristobal Vildosola, Jhon W Arenas, Agustín Laclote, Pedro Becker, Eduardo Briceño, Rodrigo González, Loreley P Bermúdez, José T Peña, Douglas Greig, Carlos E Benitez and 2 more

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Cristobal VildosolaSchool of Medicine, Pontificia Universidad Católica de Chile, Santiago, CHL.
Jhon W ArenasDepartment of Cardiology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, CHL.
Agustín LacloteSchool of Medicine, Pontificia Universidad Católica de Chile, Santiago, CHL.
Pedro BeckerSection of Cardiovascular Surgery, Division of Surgery, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, CHL.
Eduardo BriceñoDepartment of Digestive Surgery, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, CHL.
Rodrigo GonzálezSection of Cardiovascular Surgery, Division of Surgery, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, CHL.
Loreley P BermúdezDepartment of Pathology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, CHL.
José T PeñaDepartment of Pathology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, CHL.
Douglas GreigDepartment of Cardiology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, CHL.
Carlos E BenitezDepartment of Gastroenterology, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, CHL.
Ricardo RojasDepartment of Neurosurgery, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, CHL.
Jorge A MartínezDepartment of Digestive Surgery, School of Medicine, Pontificia Universidad Católica de Chile, Santiago, CHL.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Combined heart-liver transplantation (CHLT) is a rare and highly complex procedure reserved for patients with end-stage failure of both organs. We report the first successful CHLT performed in Chile, involving a 55-year-old man with severe dilated cardiomyopathy and chronic liver disease who underwent sequential bicaval heart transplantation followed by piggyback liver transplantation. The postoperative course was complicated by acute neurological deterioration due to an acute subdural hematoma with tentorial extension requiring decompressive craniectomy, after which the patient recovered fully. More than one year after transplantation, he remains in excellent health, physically active, and fully reintegrated into work, with excellent function of both grafts. This case highlights the feasibility of CHLT in Chile and underscores the importance of multidisciplinary evaluation and coordinated perioperative management in optimizing outcomes for patients with advanced multi-organ failure.

Indexed as

combined heart-liver transplantationheart transplantationimmunosuppressionliver transplantationmulti-organ failure

Identifiers

PMID41589169
PMCPMC12832033

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.