Evidence map›Paper›PMID 41588693›Full record

ReviewBioEssays : news and reviews in molecular, cellular and developmental biology2026

The Host Coral Bleaching Response Viewed Through the Lens of Multi-Omics: Multi-Omics Provides the Tools to Understand the Complex Molecular Basis of Coral Bleaching, Which Can Aid Conservation Efforts.

Debashish Bhattacharya, Shrinivas Nandi, Erin E Chille, Miriam Arroyo, Timothy G Stephens

Abstract readReview
In one paragraph

Review in BioEssays : news and reviews in molecular, cellular and developmental biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Debashish BhattacharyaDepartment of Biochemistry and Microbiology, Rutgers University, New Brunswick, New Jersey, USA.
Shrinivas NandiMicrobial Biology Graduate Program, Rutgers University, New Brunswick, New Jersey, USA.
Erin E ChilleEcology and Evolution Graduate Program, Rutgers University, New Brunswick, New Jersey, USA.
Miriam ArroyoMicrobial Biology Graduate Program, Rutgers University, New Brunswick, New Jersey, USA.
Timothy G StephensDepartment of Biochemistry and Microbiology, Rutgers University, New Brunswick, New Jersey, USA.

Funding

Catalyst Science Fund, Revive & Restore, and the National Philanthropic Trust 23-7825575National Science Foundation 2128073USDA National Institute of Food and Agriculture Hatch Formula NJ01180
6 · The paper itself

Abstract

We review recent multi-omics analyses of the coral heat stress response to explore the generality of the Oxidative Theory of Coral Bleaching (OTCB), which posits that algal symbiont release is the final act of defense by the coral host to survive alga-derived oxidative stress. The OTCB is particularly relevant given that ocean warming, which is accelerating under climate change, has proven devastating for corals, leading to the bleaching phenotype and widespread reef loss. Multi-omics results, in combination with other data, such as genome-wide association studies, support the idea that coral bleaching is a multifactorial response that reflects a wide array of causes and effects and is population-specific under most conditions, with coral ploidy and genotype being critical to bleaching sensitivity. This perspective leverages the location, algal and prokaryotic microbiome, and host genotype-specific aspects of coral resilience to promote a new "personal genomics" approach to coral conservation, analogous to that used in human health.

Indexed as

AnthozoaCoral BleachingAnimalsClimate ChangeConservation of Natural ResourcesCoral ReefsMultiomicsOxidative StressSymbiosiscoral bleachingcoral reefsdysbiosisholobiontmulti‐omicsocean warmingreactive oxygen speciesredox stress

Identifiers

PMID41588693
PMCPMC12835581

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.