ReviewGenetics2026
The Caenorhabditis Genetics Center Curated Special Collections: a guide to protein degradation systems.
Review in Genetics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Protein Depletion in Caenorhabditis elegans Using the Auxin-Inducible Degradation System.Methods in molecular biology (Clifton, N.J.) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
The Caenorhabditis Genetics Center is launching a new website feature-"Curated Special Collections"-designed to help researchers navigate the ever-evolving lists of strains harboring specialized genetic tools. Each collection will be assembled by experts who provide an overview of the system and curate the strains and their associated information as the collection expands. A companion review article will provide an in-depth analysis of each tool collection, including comparisons of different methods and modifications, discussion of their advantages and limitations, and practical guidance for getting started. The first collection in this series, Protein Degradation Systems, focuses on 2 protein depletion methods: (i) the auxin-inducible and (ii) ZIF-1/ZF1 degradation systems. Both methods are increasingly popular in Caenorhabditis elegans research because they allow rapid and precise temporal and spatial control over protein depletion. The inaugural collection and this companion review, together with additional collections forthcoming, will help researchers identify the most suitable approaches and strains for their experiments. Importantly, these collections will also lower the barrier for investigators primarily working in other model organisms to gain entry to the worm as a system for testing their ideas.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.