Evidence map›Paper›PMID 41588523›Full record

ReviewChinese medicine2026

Advancing the modernization of traditional Chinese medicine through artificial intelligence and multimodal data integration.

Pengfei Guo, Mengmeng Jiang, Shengquan Hu, Qianqian Jiang, Limin Li, Junhong Wu, Yucui Ma, Zhengzhi Wu

Abstract readReview
In one paragraph

Review in Chinese medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pengfei GuoThe First Affiliated Hospital of Shenzhen University, Shenzhen, 518035, China.
Mengmeng JiangThe First Affiliated Hospital of Shenzhen University, Shenzhen, 518035, China.
Shengquan HuThe First Affiliated Hospital of Shenzhen University, Shenzhen, 518035, China.
Qianqian JiangThe First Affiliated Hospital of Shenzhen University, Shenzhen, 518035, China.
Limin LiThe First Affiliated Hospital of Shenzhen University, Shenzhen, 518035, China.
Junhong WuThe First Affiliated Hospital of Shenzhen University, Shenzhen, 518035, China.
Yucui MaThe First Affiliated Hospital of Shenzhen University, Shenzhen, 518035, China.
Zhengzhi WuThe First Affiliated Hospital of Shenzhen University, Shenzhen, 518035, China. szwzz001@163.com.

Funding

Innovative Research Group Project of the National Natural Science Foundation of China 81574038Shenzhen Science and Technology Innovation Program JCYJ20220818101806014Shenzhen Team-based Medical Science Research Program 2024YZZ11the Ministry of Science and Technology of China 2017ZX09301001
6 · The paper itself

Abstract

Traditional Chinese Medicine (TCM) is a valuable medical treasure trove that not only demonstrated unique advantages in treating complex and refractory diseases but also left behind a rich legacy of ancient texts and valuable evidence-based medical data based on its human experience for future generations. Nevertheless, the extensive data within TCM has been plagued by challenges, including inadequate data standardization, inconsistent data quality, limited data structuring, and obstacles in interdisciplinary integration. Recent advancements in artificial intelligence (AI) techniques have markedly improved the efficiency and effectiveness with which multimodal data in TCM, including machine learning (ML), deep learning (DL), knowledge graphs (KG), and natural language processing (NLP), particularly large language models (LLMs). These advancements have facilitated more precise data analysis, enhanced clinical decision-making, and improved research outcomes in TCM, such as target discovery, virtual screening of natural products (NPs), symptom differentiation and auxiliary prescription. This article presents a comprehensive review of the progress in applying AI across four dimensions: multiscale data in TCM, TCM research and development, TCM diagnosis and treatment, and LLMs. In summary, the application of AI technology in the modernization of TCM is expected to motivate researchers to achieve a deeper understanding of state-of-the-art applications in data-driven TCM complex systems, fundamental scientific research, and precision medicine, thereby bringing more opportunities and innovations for the modernization of TCM.

Indexed as

Artificial intelligence (AI)Knowledge graphLarge language modelsNatural language processingTraditional Chinese Medicine

Identifiers

PMID41588523
PMCPMC12833950

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.