Evidence map›Paper›PMID 41588432›Full record

ArticleJournal of medical case reports2026

Electrochemotherapy in the treatment of basal cell carcinoma of the head and neck: a case report.

Gianluca Nicolai, Francesco Campanella, Sergio Alexandre Gehrke, Spinelli Raffaele, Antonio Scarano

Abstract readCase Reports
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Article in Journal of medical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Gianluca NicolaiDepartment of Maxillo-Facial Surgery, University of Tor Vergata, Rome, Italy.
Francesco CampanellaDepartment of Maxillo-Facial Surgery, University of Tor Vergata, Rome, Italy.
Sergio Alexandre GehrkeDepartment of Biotechnology, Universidad Católica de Murcia (UCAM), 30107, Murcia, Spain.
Spinelli Raffaele
Antonio ScaranoDepartment of Innovative Technology in Medicine and Dentistry, University of Chieti-Pescara, Via Dei Vestini 31, 66100, Chieti, Italy. ascarano@unich.it.ORCID http://orcid.org/0000-0003-1374-6146

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSkin areas chronically exposed to solar radiation, such as the face, neck, scalp, and upper limbs, are at significantly increased risk of developing basal cell carcinoma. The objective of this case report is to describe the treatment of a basal cell carcinoma located on the chin using electrochemotherapy in a patient with advanced heart disease, a condition that contraindicated invasive surgical intervention. CASE PRESENTATION: An 83-year-old Caucasian female patient presented with a persistent nodular lesion on the chin, present for approximately 6 months. The diagnosis of cutaneous basal cell carcinoma was confirmed through histopathological analysis of tissue obtained via punch biopsy of the lesion. A single electrochemotherapy application was sufficient. Monitoring was discontinued at 24 months due to the patient's death from cardiac causes. Her clinical condition did not allow for further diagnostic procedures such as biopsy or positron emission tomography-computed tomography.

conclusionIn the present study, the patient successfully underwent a single session of electrochemotherapy, with a favorable outcome and no complications. The therapeutic approach allowed us to avoid general anesthesia while ensuring effective treatment of the neoplastic lesion with excellent aesthetic outcomes.

Indexed as

Antibiotics, AntineoplasticBasal Cell CarcinomaBleomycinElectrochemotherapyHead and Neck NeoplasmsSkin NeoplasmsAged, 80 and overChinFemaleHumansTreatment OutcomeAntibiotics, AntineoplasticBleomycinBasal cell carcinomaBleomycinElectrochemotherapyIntralesionalNonmelanoma skin cancer

Identifiers

PMID41588432
PMCPMC12918073

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