Evidence map›Paper›PMID 41588426›Full record

ArticleMicrobial cell factories2026

Imperatives for anaerobic high cell density culturing by denitrification: technical and physiological perspectives.

Marte Mølsæter Maråk, Ingrid Malien Duister, Lars Reier Bakken, Linda Liberg Bergaust

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbial cell factories, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marte Mølsæter MaråkFaculty of Biotechnology, Chemistry and Food Science, Norwegian University for Life Sciences, Ås, Norway.
Ingrid Malien DuisterFaculty of Biotechnology, Chemistry and Food Science, Norwegian University for Life Sciences, Ås, Norway.
Lars Reier BakkenFaculty of Biotechnology, Chemistry and Food Science, Norwegian University for Life Sciences, Ås, Norway.
Linda Liberg BergaustFaculty of Biotechnology, Chemistry and Food Science, Norwegian University for Life Sciences, Ås, Norway. linda.bergaust@nmbu.no.

Funding

Novo Nordic Foundation NNF21OC0067044Research Council of Norway 333879
6 · The paper itself

Abstract

backgroundSingle-cell protein (SCP) is gaining attention as a source of food and feed, offering a lower environmental footprint than traditional agriculture. Efficient SCP production requires high cell density culturing (HCDC; >20 g cell dry weight L

resultsUsing the model organisms Paracoccus denitrificans and Paracoccus pantotrophus, we achieved biomass concentrations of up to 60 g dry weight L

conclusionsAnaerobic HCDC by denitrification is feasible and yields high-quality biomass, but barriers remain to achieving competitive production rates. The CO

Indexed as

DenitrificationParacoccus denitrificansAnaerobiosisBatch Cell Culture TechniquesBiomassBioreactorsCarbon DioxideHydrogen-Ion ConcentrationNitratesNitritesCarbon DioxideNitratesNitritesDenitrificationGrowth constraintsHigh cell density cultivation

Identifiers

PMID41588426
PMCPMC12918325

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.