ArticleBMC surgery2026
Laparoscopic cholecystectomy after gallbladder preservation: TG18 Delphi score quantifies surgical difficulty.
Article in BMC surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundDespite cultural preferences for organ preservation in East Asia, choledochoscopic gallbladder-preserving surgery (CGPS) remains controversial given high recurrence rates. This study objectively quantified the increased technical complexity of laparoscopic cholecystectomy (LC) for recurrent cholecystolithiasis after prior CGPS using the Tokyo Guidelines 2018 (TG18).
methodsIn this propensity-matched study (1:1, n = 220) conducted between 2020 and 2025, patients requiring LC due to recurrent cholecystolithiasis after prior CGPS were compared with patients with primary cholecystolithiasis undergoing LC. Investigators matched groups for TG18 severity grading, BMI, and biliary anomalies. Two blinded surgeons assessed the intraoperative findings using TG18 Delphi scoring (7-point scale). Primary outcomes included difficulty scores, critical view of safety (CVS) achievement, and bile duct injury.
resultsThe CGPS group demonstrated significantly higher median TG18 scores (34 [IQR 30–39] vs. 21 [18–24]; adjusted mean difference: Δ 14.0 points, 95% CI: 11.2–16.8; p < 0.001), primarily due to fibrotic adhesions: Calot’s triangle dense fibrosis (49.1% vs. 6.4%), partial scarring (21.8% vs. 0.9%), and diffuse scarring (15.5% vs. 0%; all p < 0.001). Surgeons achieved CVS less frequently in the CGPS group (83.6% vs. 98.2%, p < 0.001). TG18 scores > 25 predicted a fivefold increased conversion risk (aOR = 4.9, 95% CI: 2.3–10.6).
conclusionsPrior CGPS induces irreversible fibrosis that significantly increases reoperative difficulty (Δ 14 TG18 points), highlighting the need for careful patient selection in organ-preserving procedures. Definitive management with primary cholecystectomy remains the gold standard.
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