Evidence map›Paper›PMID 41588348›Full record

ArticleBMC cardiovascular disorders2026

Transcatheter aortic valve replacement in right aortic arch with mirror image branching.

Prem Patel, Waqas Qureshi, Nikolaos Kakouros

Abstract readCase Reports
In one paragraph

Article in BMC cardiovascular disorders, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Prem PatelDepartment of Medicine, University of Massachusetts Chan Medical School, Worcester, MA, United States. prem.patel8@umassmed.edu.
Waqas QureshiDivision of Cardiovascular Medicine, Houston Methodist Hospital, Baytown, TX, USA.
Nikolaos KakourosDivision of Cardiovascular Medicine, Department of Medicine, UMass Memorial Medical Center, University of Massachusetts Chan Medical School, Worcester, MA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA right aortic arch withmirror-image branching is a rare congenital anomaly resulting from the abnormal regression ofthe embryonic left aortic arch. This variant, in which the aortic arch courses to the right of the trachea and gives rise to its branches in a mirrored configuration compared to the standard left-sided arch, can present unique challenges during cardiovascular interventions such as transcatheter aortic valve replacement (TAVR). CASE REPORT: We describe a 75-year-old male undergoing evaluation for TAVR who was incidentally found to have a right aortic arch with mirror-image branching. This anomaly, characterized by a mirrored branching pattern of the arch vessels, required tailored imaging and procedural considerations. The patient successfully underwent TAVR through the right aortic arch without complications, demonstrating the adaptability of contemporary structural heart interventions.

conclusionsThis patient presented with an embryonic right aortic arch with mirror-image branching (RAA-MIB) and persistence of the left sixth arch. Given the potential technical challenges in catheter navigation that the unique anatomy of this aortic arch poses, it is critical to understand these embryological variations for successful procedural planning and execution. Clinical implications include a potentially increased risk of stroke and dissection. Advances in imaging modalities continue to enhance our ability to diagnose and manage rare aortic arch anomalies, ultimately improving patient outcomes.

Indexed as

Aorta, ThoracicAortic ValveAortic Valve StenosisTranscatheter Aortic Valve ReplacementVascular MalformationsAgedAnatomic VariationAortographyComputed Tomography AngiographyHumansIncidental FindingsMaleTreatment OutcomeCongenital Vascular AnomalyMirror-Image BranchingRight Aortic ArchStructural Heart InterventionTranscatheter Aortic Valve Replacement

Identifiers

PMID41588348
PMCPMC12958657

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.