Trial reportClinical oral investigations2026
Volumetric evaluation of the entire papilla preservation technique and the non-incised papillae surgical approach: effects on soft tissue preservation and periodontal regeneration.
Trial report in Clinical oral investigations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04782921 (Clinical Outcomes of Papillae Tunneling Techniques in the Treatment of Isolated Intrabony Defects - a Prospective, Double Blind, Randomised Clinical Trial), which is not on this map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Clinical Outcomes of Papillae Tunneling Techniques in the Treatment of Isolated Intrabony Defects - a Prospective, Double Blind, Randomised Clinical Trial
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
objectivesThis randomized, controlled clinical trial compared two minimally invasive surgical techniques - the Non-Incised Papillae Surgical Approach (NIPSA) and the Entire Papilla Preservation Technique (EPPT) - in terms of their efficacy in preserving soft tissue architecture and promoting periodontal regeneration. MATERIALS AND
methodsIsolated intrabony defects of 40 patients with stage III/IV periodontitis were randomly assigned to either NIPSA or EPPT treatment. Clinical parameters including probing depth (PD), clinical attachment level (CAL), gingival recession (REC) and papilla height (TP) were evaluated at baseline and 6-months postoperatively.
resultsBoth NIPSA and EPPT showed significant improvements in PD (5.3 ± 2.3 mm vs. 4.6 ± 1.7 mm) and CAL (4.4 ± 2.2 mm vs. 3.7 ± 1.9 mm), with no statistically significant differences between the groups. Early wound healing was favorable in both techniques, with minimal fibrin clot formation and no biomaterial exposure. Digital analysis of intraoral scans showed comparable preservation of papilla height and width in both groups. Radiographic analyses confirmed defect filling in both groups.
conclusionsBoth NIPSA and EPPT are effective surgical options for the periodontal regeneration of deep intrabony defects, offering excellent soft tissue preservation and clinical outcomes. NCT04782921. CLINICAL RELEVANCE: Both techniques remain viable, with the choice depending on the specifics of each defect and the surgeon’s preference.
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