Evidence map›Paper›PMID 41588208›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2026

Evaluating chronic bone and soft tissue infections with [

Dilara Denizmen Zorba, Duygu Has Simsek, Yasemin Sanli, Muhammet Ibrahim Karacam, Omer Naci Ergin, Arif Atahan Cagatay, Fikret Buyukkaya, Serkan Kuyumcu

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Dilara Denizmen ZorbaIstanbul Faculty of Medicine, Department of Nuclear Medicine, Istanbul University, Istanbul, Turkey. dilaradenizmen@gmail.com.ORCID 0000-0002-8270-9480
Duygu Has SimsekIstanbul Faculty of Medicine, Department of Nuclear Medicine, Istanbul University, Istanbul, Turkey.ORCID 0000-0001-6945-2003
Yasemin SanliIstanbul Faculty of Medicine, Department of Nuclear Medicine, Istanbul University, Istanbul, Turkey.ORCID 0000-0002-1267-2379
Muhammet Ibrahim KaracamIstanbul Faculty of Medicine, Department of Orthopedics and Traumatology, Istanbul University, Istanbul, Turkey.ORCID 0009-0002-4766-8481
Omer Naci ErginIstanbul Faculty of Medicine, Department of Orthopedics and Traumatology, Istanbul University, Istanbul, Turkey.ORCID 0000-0001-6848-6930
Arif Atahan CagatayIstanbul Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Istanbul University, Istanbul, Turkey.ORCID 0000-0002-3051-8199
Fikret BuyukkayaIstanbul Faculty of Medicine, Department of Nuclear Medicine, Istanbul University, Istanbul, Turkey.ORCID 0000-0002-9766-1491
Serkan KuyumcuIstanbul Faculty of Medicine, Department of Nuclear Medicine, Istanbul University, Istanbul, Turkey.ORCID 0000-0002-1158-5361

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeChronic bone and soft tissue infections pose a diagnostic challenge, as conventional imaging techniques often show limited sensitivity and specificity. Given that CXCR4 chemokine receptors are expressed on lymphocytes, key mediators of chronic inflammatory response, we hypothesized that CXCR4-targeted imaging may offer enhanced diagnostic accuracy. Accordingly, this study aimed to evaluate the diagnostic performance of [

methodsIn this retrospective single-centre study, we included patients who underwent both conventional scintigraphic imaging and [

resultsA total of 20 patients with 25 suspected infectious foci and 14 control sites were evaluated. Of the 25 sites, 21 were confirmed to be infected; no infections were observed in the control sites. Scintigraphy correctly identified 19 infection sites (sensitivity: 90%, specificity: 83%), while [

conclusion[

Indexed as

Coordination ComplexesPeptides, CyclicPositron Emission Tomography Computed TomographySoft Tissue InfectionsAdultAgedAged, 80 and overChronic DiseaseFemaleGallium RadioisotopesHumansMaleMiddle AgedRetrospective Studies68Ga-pentixaforCoordination ComplexesGallium RadioisotopesPeptides, Cyclic[68Ga]Ga-Pentixafor PET/CTChronic infectionCXCR4Diabetic foot infectionLabelled leucocyte scintigraphyPeriprosthetic infection

Identifiers

PMID41588208
PMCPMC13013284

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.