ArticleNature2026
Scalable and multiplexed recorders of gene regulation dynamics across weeks.
Abstract read
In one paragraph
Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Simultaneous brain-wide single-cell recording resolves spatiotemporal memory architecture.bioRxiv : the preprint server for biology · 2026Article
- Article
Corrections and comments
- Update of
Authors and funding
23 authors.
Lirong Zheng *Department of Cell and Developmental Biology, Medical School, University of Michigan, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0001-6803-5048
Dongqing Shi *Department of Cell and Developmental Biology, Medical School, University of Michigan, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0002-8687-2701
Yixiao Yan *Department of Cell and Developmental Biology, Medical School, University of Michigan, Ann Arbor, MI, USA.
Bingxin ZhouDepartment of Computer Science and Technology, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-3897-9766
Jormay LimDepartment of Cell and Developmental Biology, Medical School, University of Michigan, Ann Arbor, MI, USA.
Yongjie HouDepartment of Cell and Developmental Biology, Medical School, University of Michigan, Ann Arbor, MI, USA.
Bobae AnMcGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
Jason K AdhinartaDepartment of Computer Science, Boston College, Boston, MA, USA.ORCID http://orcid.org/0000-0002-6247-7475
Michael LinDepartment of Computer Science, Boston College, Boston, MA, USA.
BumJin KoNash Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
William C JoestenDepartment of Cell and Developmental Biology, Medical School, University of Michigan, Ann Arbor, MI, USA.
Mehul GautamDepartment of Cell and Developmental Biology, Medical School, University of Michigan, Ann Arbor, MI, USA.ORCID http://orcid.org/0009-0009-9076-770X
Elie D M HuezKresge Hearing Research Institute and Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0003-0696-564X
Eung Chang KimMcGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
Emily G KlyderDepartment of Chemistry, University of Michigan, Ann Arbor, MI, USA.
Boxuan ChangDepartment of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI, USA.
Sethuramasundaram PitchiayaDepartment of Urology, University of Michigan, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0003-2529-5186
Michael T RobertsKresge Hearing Research Institute and Department of Otolaryngology-Head and Neck Surgery, University of Michigan, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0003-2835-8752
Denise J CaiNash Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID http://orcid.org/0000-0002-7729-0523
Edward S BoydenMcGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
Donglai WeiDepartment of Computer Science, Boston College, Boston, MA, USA.ORCID http://orcid.org/0000-0002-2329-5484
Pietro LiòDepartment of Computer Science and Technology, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-0540-5053
Changyang LinghuDepartment of Cell and Developmental Biology, Medical School, University of Michigan, Ann Arbor, MI, USA. linghu@umich.edu.ORCID http://orcid.org/0000-0002-7481-5275
Funding
Expansion MicroscopyR01EB024261 · NIBIB · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BOYDEN, EDWARD S. · 2017 to 2025
$4.6MMultidimensional Optimization of Voltage Indicators for In Vivo Neural Activity ImagingR01MH122971 · NIMH · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI HAN, XUE · 2020 to 2024
$3.4MMechanisms of pathology and neuronal hyperactivity in a memory circuit in Alzheimer's diseaseR01AG070831 · NIA · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI BOYDEN, EDWARD S., TSAI, LI-HUEI · 2021 to 2025
$3.2MEarly Stage Training in the NeurosciencesT32NS076401 · NINDS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Carol Fuzeti Elias, LESLIE S. SATIN · 2011 to 2026
$3.1MLipid imaging expansion microscopy to study Alzheimer's diseaseR01AG087374 · NIA · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI Edward S. Boyden, Li-Huei Tsai · 2024 to 2026
$2.3MMultidisciplinary Research Training in Sleep ScienceT32HL160511 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI INDU A AYAPPA, ANDREW W VARGA · 2023 to 2026
$1.5MTemporally scalable recording of brain-wide single-cell physiologyDP2MH140133 · NIMH · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LINGHU, CHANGYANG · 2024 to 2024
$1.3MNHLBI NIH HHS T32 HL160511NIA NIH HHS R01 AG070831NIA NIH HHS R01 AG087374NIBIB NIH HHS R01 EB024261NIMH NIH HHS DP2 MH140133NIMH NIH HHS R01 MH122971NINDS NIH HHS T32 NS076401
Abstract
Gene expression is dynamically controlled by gene regulatory networks comprising multiple regulatory components to mediate cellular functions
Indexed as
Gene Expression RegulationSingle-Cell AnalysisAnimalsBrainDoxycyclineFemaleGene Regulatory NetworksGenes, Immediate-EarlyHumansMicePromoter Regions, GeneticSpatio-Temporal AnalysisTime FactorsTranscription FactorsTranscription, GeneticDoxycyclineTranscription Factors
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.