Observational studyJournal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
Correlation Between Peripheral Blood Inflammatory Markers and Obstructive Sleep Apnea Severity.
Observational study in Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- A crosstalk between the immune system and obstructive sleep apnea.Frontiers in immunology · 2026Review
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
ImportancePeripheral blood inflammatory indices provide a noninvasive and cost-effective means to assess systemic inflammation. This study highlights the potential of pan-immune-inflammation value (PIV) as a reliable biomarker for obstructive sleep apnea (OSA) severity, with implications for clinical risk stratification.ObjectiveTo evaluate the association between peripheral blood inflammatory markers and OSA severity and identify predictive biomarkers for disease classification.DesignProspective observational study.SettingSingle tertiary academic medical center (Peking University Third Hospital), outpatient sleep clinic.Participants266 adults with snoring (18-70 years) undergoing sleep monitoring, laryngoscopy, and blood tests. Exclusion criteria included recent infection, systemic illness, surgery, or pregnancy.Intervention or ExposuresNo therapeutic intervention was performed. Exposures included varying severities of OSA and soft palate obstruction assessed by the Müller maneuver. Inflammatory indices (PIV, SIRI, SIL, neutrophil-to-lymphocyte ratio, monocyte-to-lymphocyte ratio [MLR], and platelet-to-lymphocyte ratio) were calculated from routine blood parameters.Main Outcome MeasuresThe primary outcome was the association between inflammatory indices and OSA severity as measured by apnea-hypopnea index (AHI). Secondary outcome was the correlation between inflammatory markers and soft palate-level obstruction.ResultsPIV and SIRI were significantly elevated in severe OSA cases (
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