ArticleNeotropical entomology2026
First Detection of the L1014F kdr Mutation in Triatoma dimidiata, a Vector of Chagas Disease in Mexico.
Article in Neotropical entomology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Chagas disease remains a major public health problem in Latin America, with Triatoma dimidiata (Latreille, 1811) recognized as one of the principal vectors in Mexico. The prolonged use of pyrethroids for vector control has raised concerns about the emergence of resistance, often associated with knockdown resistance (kdr) mutations in the voltage-gated sodium channel (VGSC). Monitoring insecticide susceptibility and identifying associated resistance mechanisms are, therefore, critical for effective surveillance and control. In this study, we evaluated the susceptibility of T. dimidiata from Yucatan, Mexico, to deltamethrin and permethrin using topical application bioassays and sequenced VGSC domain II to detect potential kdr substitutions. We report, for the first time in T. dimidiata, the presence of the L1014F mutation in a population exhibiting resistance to permethrin (RR
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