A Novel NIR Fluorescent Probe with Large Stokes Shift for the Detection of Hg

Huan Zhang, Limeng Cong, Cong Sun, Jinwei Zhang, Shuai Guo, Songhua Zhu, Baoze Guo, Junqing Zhou, Youlai Zhang

Abstract read

In one paragraph

Article in Journal of fluorescence, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Huan ZhangTianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion, School of Chemistry and Chemical Engineering, Tianjin University of Technology, Tianjin, 300384, P. R. China.

Limeng CongTianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion, School of Chemistry and Chemical Engineering, Tianjin University of Technology, Tianjin, 300384, P. R. China.

Cong SunTianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion, School of Chemistry and Chemical Engineering, Tianjin University of Technology, Tianjin, 300384, P. R. China.

Jinwei ZhangTianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion, School of Chemistry and Chemical Engineering, Tianjin University of Technology, Tianjin, 300384, P. R. China.

Shuai GuoTianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion, School of Chemistry and Chemical Engineering, Tianjin University of Technology, Tianjin, 300384, P. R. China.

Songhua ZhuTianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion, School of Chemistry and Chemical Engineering, Tianjin University of Technology, Tianjin, 300384, P. R. China.

Baoze GuoTianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion, School of Chemistry and Chemical Engineering, Tianjin University of Technology, Tianjin, 300384, P. R. China.

Junqing ZhouTianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion, School of Chemistry and Chemical Engineering, Tianjin University of Technology, Tianjin, 300384, P. R. China.

Youlai ZhangTianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion, School of Chemistry and Chemical Engineering, Tianjin University of Technology, Tianjin, 300384, P. R. China. youlai@tjut.edu.cn.

Funding

National Natural Science Foundation of China 22203063Natural Science Foundation of Tianjin Municipality 20JCYBJC00410

6 · The paper itself

Abstract

Mercury (Hg) ranks among the most hazardous metals. Hg2+ contamination has grown to be a major concern for people worldwide. Thus, it is crucial to discover a quick, practical, and reliable method of Hg2+ testing for both human health and the ecological environment. In the present study, a NIR fluorescent probe TP-Hg was designed for Hg2+ detection based on thiopyran tetracarbonitrile by employing the Hg2+-triggered thioacetal deprotection reaction. Spectral experimental results demonstrated TP-Hg possessed excellent selectivity toward Hg2+ (λex/em = 563/770 nm), with good sensitivity (LOD = 0.13 µM) and high anti-interference performance. Bioimaging assays showed that the probe TP-Hg enabled accurate detection of Hg2+ in living cells and zebrafish. Moreover, this probe was successfully applied to detect Hg2+ on test strips.

Indexed as

Fluorescent DyesMercuryOptical ImagingAnimalsFluorescent Chemosensor CompoundsHeLa CellsHumansSpectroscopy, Near-InfraredZebrafishFluorescent Chemosensor CompoundsFluorescent DyesMercuryBioimagingHg2+ detectionLarge stokes shiftNIR fluorescent probeTest strips

Identifiers

PMID41586969

DOI10.1007/s10895-025-04698-w

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.