ArticleJournal of neuro-oncology2026
High-risk morphology in cystic vestibular schwannomas: an imaging-based scoring system for facial nerve outcomes.
Article in Journal of neuro-oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeFacial nerve (FN) preservation in vestibular schwannoma (VS) remains challenging, and outcomes in cystic VS are inconsistent. This study aimed to identify cyst-specific imaging features defining a high-risk subset predictive of postoperative FN dysfunction.
methodsA retrospective cohort of patients who underwent VS resection (2002–2024) was analyzed. Morphological characteristics of the cystic components on preoperative magnetic resonance imaging were classified as central or peripheral types, with peripheral cysts subclassified by anatomical direction. Logistic regression identified predictors of poor FN outcome (House–Brackmann [HB] grade ≥ III).
resultsOf 266 patients, 77 (29.8%) had cystic VS. Among these, 18.2% were central type and 81.8% peripheral type; anterior, medial, and posterior components were present in 51.9%, 68.8%, and 62.3%, respectively. Poor short-term FN outcomes occurred in 19 patients (24.7%) and were associated with absence of the fundal fluid cap (FFC) sign (63.2% vs. 25.9%, p = 0.005), anterior cerebellopontine angle (CPA) subtype (84.2% vs. 31.0%, p < 0.001), anterior peripheral cysts (73.7% vs. 44.8%, p = 0.036), and internal auditory canal cyst extension (15.8% vs. 1.7%, p = 0.044). Extent of resection did not differ between outcome groups. Multivariate analysis identified absence of the FFC sign (OR 8.75), anterior CPA subtype (OR 21.9), and anterior peripheral cysts (OR 6.92) as independent predictors of poor FN outcome. A risk stratification integrating these features demonstrated excellent discrimination (AUC 0.853). High-risk patients experienced significantly worse short- and long-term FN outcomes (preservation rates of good FN function [HB grade I–II]: 40.7% vs. 94.0%, p < 0.001; 81.5% vs. 96.0% at 12 months, p = 0.048).
conclusionsAnterior peripheral cyst morphology, together with absence of the FFC sign and anterior CPA subtype, defines a high-risk subset of cystic VS strongly associated with unfavorable FN outcomes, supporting improved preoperative risk stratification.
Indexed as
Identifiers
41586950What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.