Evidence map›Paper›PMID 41586942›Full record

ArticlePlant foods for human nutrition (Dordrecht, Netherlands)2026

Substitution of Salt with Choline Chloride in Double-Layer Flatbreads: Impact on Technological Properties and Starch Digestibility.

Maria Santamaria, Clara Leguet, Nour Doumani, Patricia Le-Bail, Cristina M Rosell

Abstract read
In one paragraph

Article in Plant foods for human nutrition (Dordrecht, Netherlands), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maria SantamariaInstitute of Agrochemistry and Food Technology (IATA-CSIC), C/Agustin Escardino, 7, Paterna, Valencia, 46980, Spain.ORCID http://orcid.org/0000-0001-9167-098X
Clara LeguetBiopolymères Interactions Assemblages, INRAE, EUR 1268, BP 71627, Nantes, Cedex, 3F- 44316, France.
Nour DoumaniBiopolymères Interactions Assemblages, INRAE, EUR 1268, BP 71627, Nantes, Cedex, 3F- 44316, France.ORCID https://orcid.org/0000-0002-3633-7831
Patricia Le-BailBiopolymères Interactions Assemblages, INRAE, EUR 1268, BP 71627, Nantes, Cedex, 3F- 44316, France.
Cristina M RosellInstitute of Agrochemistry and Food Technology (IATA-CSIC), C/Agustin Escardino, 7, Paterna, Valencia, 46980, Spain. crosell@iata.csic.es.ORCID http://orcid.org/0000-0001-7197-5874

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The association of sodium intake with hypertension has prompted the salt reduction in food processing. However, salt reduction is technologically challenging in process like breadmaking. The aim of this study was to identify the impact of salt reduction on the dough properties, technological characteristics and in vitro digestion on gluten and gluten-free flatbreads. In addition, the inclusion of choline chloride, (E 1001) as salt replacer (25% choline chloride substitution) was explored. Gluten-free dough exhibited higher hardness than gluten dough due to the predominance of gelatinized starch. Salt reduction gluten-free dough presented lower hardness because of the hydrophobicity of the rice proteins. The texture of the flatbreads was not affected by the addition of choline chloride, with control and choline chloride-enriched flatbreads showing similar strength and extensibility. Moreover, gluten-free flatbreads with choline chloride presented lower starch hydrolysis, because of the ionic compound (choline chloride) on starch gelatinization, which increases the viscosity of the system. In conclusion, gluten-free flatbread with choline chloride could represent a potential strategy to decrease the glycemic index and mitigate hypertension in consumers of gluten-free bread.

Indexed as

BreadCholineSodium Chloride, DietaryStarchDiet, Gluten-FreeDigestionFlourFood HandlingGlutensGlycemic IndexHardnessHumansHydrolysisOryzaViscosityCholineGlutensSodium Chloride, DietaryStarchBreadBreadmakingGluten, gluten-freeSalt reductionStarch hydrolysis

Identifiers

PMID41586942
PMCPMC12835044

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.