Evidence map›Paper›PMID 41586588›Full record

ArticleHuman vaccines & immunotherapeutics2026

Dynamics of anal HPV infection after 9vHPV vaccination in men who have sex with men (MSM) with HIV: A prospective, controlled cohort study.

Kuan-Yin Lin, Shuo-Lun Lai, Yu-Shan Huang, Hsin-Yu Sun, Yu-Chung Chuang, I-Shiow Jan, Wen-Chun Liu, Chi-Tai Fang, Chien-Ching Hung

Abstract read
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In one paragraph

Article in Human vaccines & immunotherapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kuan-Yin LinDepartment of Internal Medicine, National Taiwan University Hospital and National Taiwan, University College of Medicine, Taipei, Taiwan.
Shuo-Lun LaiDepartment of Surgery, National Taiwan University Hospital and National Taiwan, University College of Medicine, Taipei, Taiwan.
Yu-Shan HuangDepartment of Internal Medicine, National Taiwan University Hospital and National Taiwan, University College of Medicine, Taipei, Taiwan.
Hsin-Yu SunDepartment of Internal Medicine, National Taiwan University Hospital and National Taiwan, University College of Medicine, Taipei, Taiwan.
Yu-Chung ChuangDepartment of Internal Medicine, National Taiwan University Hospital and National Taiwan, University College of Medicine, Taipei, Taiwan.
I-Shiow JanDepartment of Laboratory Medicine, National Taiwan University Hospital and National, Taiwan University College of Medicine, Taipei, Taiwan.
Wen-Chun LiuDepartment of Internal Medicine, National Taiwan University Hospital and National Taiwan, University College of Medicine, Taipei, Taiwan.
Chi-Tai FangDepartment of Internal Medicine, National Taiwan University Hospital and National Taiwan, University College of Medicine, Taipei, Taiwan.ORCID 0000-0002-7380-1699
Chien-Ching HungDepartment of Internal Medicine, National Taiwan University Hospital and National Taiwan, University College of Medicine, Taipei, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Men who have sex with men (MSM) with HIV are disproportionately affected by persistent human papillomavirus (HPV) infections and related anogenital cancers. No controlled trial has evaluated the efficacy of the nonavalent HPV vaccine (9vHPV) in this population. This prospective, controlled cohort study offered eligible MSM with HIV a 3-dose 9vHPV series and followed both the vaccinated group (vaccinees) and the unvaccinated group (controls). Anal specimens were collected for HPV genotyping, cytology, and microbiota profiling. The primary outcomes were the clearance and incidence of 9vHPV-covered HPV types. Baseline vaccine-type HPV prevalence was 41.0% in vaccinees (n = 39; median age, 33 y; median CD4, 682/μl) and 39.3% in controls (n = 56; median age, 35 y; median CD4, 679/μl) (

Indexed as

Anal CanalAnus DiseasesHIV InfectionsHomosexuality, MaleHuman Papillomavirus VirusesPapillomavirus InfectionsPapillomavirus VaccinesAdultGenotypeHumansIncidenceMaleMiddle AgedPapillomaviridaePrevalenceProspective StudiesHuman Papillomavirus Recombinant Vaccine nonavalentPapillomavirus Vaccinesanal cancer screeninganal cytologyClearancemicrobiotaprecancerous lesionregressionsexually transmitted infection

Identifiers

PMID41586588
PMCPMC12851388

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.