Evidence map›Paper›PMID 41586502›Full record

ArticleAntimicrobial agents and chemotherapy2026

The next-generation polyene EL219 is efficacious in an experimental model of central nervous system coccidioidomycosis caused by

Nathan P Wiederhold, Laura K Najvar, Rosie Jaramillo, Marcos Olivo, Thomas F Patterson

Erratum issuedAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Nathan P WiederholdFungus Testing Laboratory, Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.ORCID 0000-0002-2225-5122
Laura K NajvarDivision of Infectious Diseases, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Rosie JaramilloDivision of Infectious Diseases, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Marcos OlivoDivision of Infectious Diseases, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Thomas F PattersonDivision of Infectious Diseases, Department of Medicine, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.ORCID 0000-0002-9513-7127

Funding

NIH / NIAID, National Institutes of Health, Department of Health and Human Services
6 · The paper itself

Abstract

We evaluated the

Indexed as

Antifungal AgentsCoccidioidesCoccidioidomycosisPolyenesAcetamidesAnimalsBrainCoccidioidal MeningitisDisease Models, AnimalFluconazoleMicePiperazinesPyrimidinesPyrrolesAcetamidesAntifungal AgentsFluconazoleolorofimPiperazinesPolyenesPyrimidinesPyrrolesCoccidioidesspeciescoccidioidomycosisEL219

Identifiers

PMID41586502
PMCPMC12959084

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.