Evidence map›Paper›PMID 41586494›Full record

ArticleAntimicrobial agents and chemotherapy2026

A genomics-informed mechanism-based pharmacokinetic/pharmacodynamic model of cefiderocol and ceftazidime/avibactam against carbapenem-resistant

Bhavatharini Arun, Rajnikant Sharma, Quentin Vallé, Ngoc Minh Bui, Nicholas Furtado, María Soledad Ramirez, Gauri Rao

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bhavatharini ArunDepartment of Clinical Pharmacy, USC Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, California, USA.ORCID 0000-0001-7784-0241
Rajnikant SharmaDepartment of Clinical Pharmacy, USC Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, California, USA.
Quentin ValléDepartment of Clinical Pharmacy, USC Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, California, USA.
Ngoc Minh BuiDepartment of Clinical Pharmacy, USC Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, California, USA.
Nicholas FurtadoDepartment of Biological Science, Center for Applied Biotechnology Studies, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, California, USA.
María Soledad RamirezDepartment of Biological Science, Center for Applied Biotechnology Studies, College of Natural Sciences and Mathematics, California State University Fullerton, Fullerton, California, USA.ORCID 0000-0002-9904-7890
Gauri RaoDepartment of Clinical Pharmacy, USC Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, California, USA.ORCID 0000-0002-8704-7770

Funding

National Institute of Allergy and Infectious Diseases NIH R01AI146241National Institute of Allergy and Infectious Diseases R01AI170889U.S. Public Health Service SC3GM125556
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Achromobacter denitrificansAnti-Bacterial AgentsAzabicyclo CompoundsCarbapenemsCeftazidimeCephalosporinsbeta-LactamasesCefiderocolDrug CombinationsDrug Resistance, Multiple, BacterialGenomicsHumansMicrobial Sensitivity TestsThird Generation CephalosporinsAnti-Bacterial Agentsavibactam, ceftazidime drug combinationAzabicyclo Compoundsbeta-LactamasesCarbapenemsCefiderocolCeftazidimeCephalosporinsDrug CombinationsThird Generation CephalosporinsAchromobacter xylosoxidansantimicrobial resistancebacterial genomicsimmunocompromised hostsmathematical modelβ-lactams

Identifiers

PMID41586494
PMCPMC12959123

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.