Evidence map›Paper›PMID 41586400›Full record

ArticleAnnals of gastroenterology

Routine esophagogastroduodenoscopy before upper endoscopic ultrasound for non-luminal indications: clinical value and findings from a large single-center experience.

Reshad Salam, Zachary Bassler, Yash Hegde, Ola Altahan, Spencer Kitchen, Serge Sorser, Douglas G Adler

Abstract read
In one paragraph

Article in Annals of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Reshad SalamDepartment of Internal Medicine, Henry Ford Providence Hospital, Southfield, Michigan, USA (Reshad Salam, Zachary Bassler).
Zachary BasslerDepartment of Internal Medicine, Henry Ford Providence Hospital, Southfield, Michigan, USA (Reshad Salam, Zachary Bassler).
Yash HegdeDepartment of Medicine, School of Medicine & Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA (Yash Hegde).
Ola AltahanDepartment of Internal Medicine, Henry Ford Hospital, Detroit, Michigan, USA (Ola Altahan).
Spencer KitchenDepartment of Anesthesiology, Corewell Health William Beaumont University Hospital, Royal Oak, Michigan, USA (Spencer Kitchen).
Serge SorserDepartment of Gastroenterology, Peak Gastroenterology Associates, Colorado Springs, Colorado, USA (Serge Sorser).
Douglas G AdlerCenter for Advanced Therapeutic Endoscopy, Porter Adventist Hospital, Denver, CO, USA (Douglas G. Adler).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Most echoendoscopes are oblique viewing instruments, potentially limiting their value in mucosal evaluation during upper endoscopic ultrasound (EUS) examinations. This raises at least the potential for missed mucosal lesions. While esophagogastroduodenoscopy (EGD) prior to EUS may mitigate this, performing EGD adds both cost and time to upper EUS. This study evaluated the utility of routine EGD before EUS in asymptomatic patients. Methods: We performed a retrospective, single-center, cohort study including 626 patients undergoing EUS for pancreaticobiliary/mediastinal indications over a 5-year period (2017-2022). Exclusion criteria included luminal symptoms or prior upper gastrointestinal surgery. Clinically significant EGD findings and their impact on management were analyzed. Results: Among 568 patients who underwent EGD before EUS, 16.8% (n=95) had clinically significant lesions, including reflux esophagitis (32.7%), Barrett's esophagus (12.7%) and gastritis (17.3%). Additionally, 16.6% (n=94) exhibited findings affecting the feasibility of EUS (e.g., strictures, large hiatal hernias). Management changes occurred in 54.3% of cases, primarily biopsies (54.3%) and medication initiation (36.6%). Only 4.6% had a prior EGD within 6 months of their EUS. Conclusions: Routine EGD before EUS can detect clinically significant mucosal lesions in asymptomatic patients, as well as anatomical factors influencing EUS performance. These findings support considering the incorporation of routine EGD into pre-EUS evaluations to optimize diagnostic accuracy and patient management.

Indexed as

diagnostic accuracyendoscopic ultrasoundEsophagogastroduodenoscopyluminal lesionsupper gastrointestinal tract

Identifiers

PMID41586400
PMCPMC12829533

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.