Evidence map›Paper›PMID 41586372›Full record

ArticleFrontiers in microbiology2025

Investigation into skin physiological parameters and mocroflora characteristics of melasma population in Lhasa China.

Longwei Fang, Bu Luo, Deqiong Danzen, La Yang, Yun Gao, Zhen Ni, Jin Wang, Zhuoma Duoji, Yang Ci, Wangdui Suolang and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Longwei Fang *High Altitude Health Science Research Center, Tibet University, Lhasa, China.
Bu Luo *Shigatse Tibetan Hospital, Shigatse, China.
Deqiong Danzen *High Altitude Health Science Research Center, Tibet University, Lhasa, China.
La YangHigh Altitude Health Science Research Center, Tibet University, Lhasa, China.
Yun GaoLhasa People's Hospital, Lhasa, China.
Zhen NiHigh Altitude Health Science Research Center, Tibet University, Lhasa, China.
Jin WangHigh Altitude Health Science Research Center, Tibet University, Lhasa, China.
Zhuoma DuojiHigh Altitude Health Science Research Center, Tibet University, Lhasa, China.
Yang CiShigatse Tibetan Hospital, Shigatse, China.
Wangdui SuolangShigatse Tibetan Hospital, Shigatse, China.
Wang GeShigatse People's Hospital, Shigatse, China.
Zhuoma BasangHigh Altitude Health Science Research Center, Tibet University, Lhasa, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Melasma is a skin disease characterized by symmetrical pigmentation, mainly occurring in the exposed areas of the face, which has some relationship with skin parameters and bacterial diversity. High-altitude regions experience elevated ultraviolet (UV) radiation, potentially influencing skin parameters and microbial characteristics in melasma. To explore the inherent law of the melasma mechanism in high altitude, the hereditary Tibetans at high altitude in Lhasa, Tibet were investigated. Skin physiological parameters such as skin sebum (SM), corneum moisture content (CM), pH, trans epidermal water loss (TEWL), skin erythema index (E), melanin (M), individual typology angle (ITA) and so on, were measured and the microbiome characteristics were sequenced and analyzed. The results showed that among 302 participants, 36 were diagnosed with melasma (mean prevalence: 11.92%). Prevalence was significantly higher in females (16.67%) than males (2.04%), peaking in females aged 31-40 years (37.50%). Melasma patients exhibited significantly lower pH and higher M values compared to controls (

Indexed as

flora characteristicsmelasmamicrobiomeskin physiological characteristicsTibet

Identifiers

PMID41586372
PMCPMC12823952

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.