Evidence map›Paper›PMID 41586340›Full record

ArticleGastro hep advances2026

Hitoshi Tsugawa, Jin Imai, Eiji Sugiyama, Chanudporn Sugiyama, Takashi Ueda, Miwa Hirai, Kenichiro Todoroki, Hidekazu Suzuki

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gastro hep advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hitoshi TsugawaTranskingdom Signaling Research Unit, Division of Host Defense Mechanism, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
Jin ImaiInstitute of Medical Sciences, Tokai University, Isehara, Kanagawa, Japan.
Eiji SugiyamaSchool of Pharmaceutical Sciences, University of Shizuoka, Suruga-ku, Shizuoka, Japan.
Chanudporn SugiyamaSchool of Pharmaceutical Sciences, University of Shizuoka, Suruga-ku, Shizuoka, Japan.
Takashi UedaDivision of Gastroenterology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan.
Miwa HiraiDivision of Gastroenterology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan.
Kenichiro TodorokiSchool of Pharmaceutical Sciences, University of Shizuoka, Suruga-ku, Shizuoka, Japan.
Hidekazu SuzukiDivision of Gastroenterology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background AND Aims: Although Methods: Using Results: Propionate and butyrate induced capping actin protein of muscle Z-line α subunit 1 (CAPZA1) overexpression via histone deacetylase inhibition. In SCFA-induced CAPZA1-overexpressing cells, the Conclusion: SCFA-induced CAPZA1-overexpressing cells serve as a scaffold niche that supports CagA activity and promotes CD44v9-positive cancer stem-like cells. This study sheds new light on the early molecular events driving

Indexed as

AutophagyCagACancer-Stem CellsGastric Cancer

Identifiers

PMID41586340
PMCPMC12828395

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.