ArticleFrontiers in nutrition2025
Metoclopramide combined with probiotics improves gastric retention in mechanically ventilated patients following craniocerebral surgery.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
Objectives: This study aimed to evaluate the effect of the co-administration of metoclopramide and probiotics on enteral feeding tolerance in mechanically ventilated patients after cranial surgery. Methods: From January 2023 to December 2024, a total of 88 patients presenting with acute brain injury and treated by craniocerebral surgery were screened. Of these, 32 were excluded and 56 patients were enrolled and assigned to either the intervention group ( Results: Compared to the control group, the intervention group exhibited a statistically significant reduction in total gastric residual volume (GRV) during the first 3 days of gastric tube feeding (103.1 ± 47.8 ml versus 756.3 ± 137.1 ml, Conclusion: The co-administration of metoclopramide and probiotics significantly reduced gastrointestinal intolerance such as gastric retention, vomiting, and diarrhea in mechanically ventilated patients following craniocerebral surgery.
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