Evidence map›Paper›PMID 41586207›Full record

ArticleFrontiers in digital health2025

A transparent four-feature speech model for depression screening applicable across clinical and community settings, including assisted-living environments.

Kevin Mekulu, Faisal Aqlan, Hui Yang

Abstract read
In one paragraph

Article in Frontiers in digital health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Kevin MekuluComplex Systems Monitoring, Modeling and Control Laboratory, Pennsylvania State University, University Park, PA, United States.
Faisal AqlanCenter for Human Systems Engineering, University of Louisville, Louisville, KY, United States.
Hui YangComplex Systems Monitoring, Modeling and Control Laboratory, Pennsylvania State University, University Park, PA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depression in older adults, often underrecognized and frequently conflated with cognitive symptoms, remains a major challenge in settings such as assisted-living communities. However, the need for scalable, speech-based screening tools extends across diverse populations and is not restricted to older adults or residential care. Depression in older adults is both common and frequently underdiagnosed, and while assisted-living environments represent a high-need deployment context, the present model is population-agnostic and can be validated across multiple real-world settings. Depression often co-occurs with mild cognitive impairment, creating a complex and vulnerable clinical landscape. Despite this urgency, scalable, interpretable, and easy-to-administer tools for early screening remain scarce. In this study, we introduce a transparent and lightweight AI-driven screening model that uses only four linguistic features extracted from brief conversational speech to detect depression with high sensitivity. Trained on the DAIC-WOZ dataset and optimized for deployment in resource-constrained settings, our model achieved moderate discriminative performance (AUC = 0.760) with a clinically calibrated sensitivity of 92%. Beyond raw accuracy, the model offers insights into how affective language, syntactic complexity, and latent semantic content relate to psychological states. Notably, one semantic feature derived from transformer embeddings, emb_1, appears to capture deeper emotional or cognitive tension not directly expressed through lexical negativity. Although the dataset does not contain explicit cognitive-status labels, these findings motivate future research to test whether similar semantic patterns may overlap with linguistic indicators of cognitive-affective strain observed in prior work. Our approach outperforms many more complex models in the literature, yet remains simple enough for real-time, on-device use, marking a step forward in making mental health AI both interpretable and clinically actionable. The resulting framework is population-agnostic and can be validated in assisted-living environments as one of several high-need deployment settings.

Indexed as

assisted-livingdepressiondigital healthinterpretable AIlinguistic biomarkerslogistic regressionsemantic embeddingspeech analysis

Identifiers

PMID41586207
PMCPMC12823896

What OpenQuestion holds

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.