ArticleIranian journal of basic medical sciences2025
Synergistic effect of carbomer polymer and graphene oxide nanoparticles on the rat wound healing process.
Article in Iranian journal of basic medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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Authors and funding
5 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Objectives: Wound healing is a multifaceted process involving inflammation, proliferation, and remodeling phases. Effective wound management requires materials that can promote tissue regeneration while preventing infections. Carbomer polymers are widely used in wound dressings due to their biocompatibility and water absorption properties, while graphene oxide nanoparticles have shown potential in enhancing cellular activities and antimicrobial effects. However, the combined effect of these materials on wound healing remains unexplored. Materials and Methods: A composite hydrogel was prepared by incorporating graphene oxide nanoparticles into a carbomer polymer matrix. The hydrogel's physicochemical properties, including swelling behavior, mechanical strength, and drug release profile, were evaluated. Results: The composite hydrogel demonstrated superior swelling capacity and mechanical stability. Conclusion: The synergistic combination of carbomer polymer and graphene oxide nanoparticles effectively enhances wound healing by improving hydrogel properties and promoting tissue regeneration. This composite material holds significant potential for advanced wound care applications.
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