ArticleMetabolism open2026
Evaluation of in vitro and in vivo antidiabetic potential of hydromethanol extract and solvent fraction of the leaves of
Article in Metabolism open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Diabetes mellitus is a spectrum of distinct metabolic disorders marked by sustained elevation of blood glucose levels that arises from deficiencies in either insulin action, insulin secretion, or a combination of both. Objective: To evaluate the antidiabetic effects of hydromethanol and solvent fraction extracts from the leaves of Method: The plant leaves were extracted using the maceration technique. The plant's acute oral toxicity test was evaluated according to the guidelines of the Organization for Economic Cooperation and Development. In vitro α-amylase inhibition activity of the hydromethanol and solvent fraction extracts of the leaves of Result: An acute toxicity study of the hydromethanol extract of the leaves of the Conclusion: Acute treatment with hydromethanol extract is safe and well-tolerated when administered orally. The study supported the traditional use of
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