Evidence map›Paper›PMID 41586118›Full record

ArticleJournal of reproduction & infertility

Impact of Intrauterine Growth Restriction on Fetal Cortical Brain Development: A Neurosonographic Assessment at 28-36 Weeks of Gestation.

Behrokh Sahebdel, Reihaneh Mortazavi Ardestani, Setareh Soltani, Mohammad Hossein Golezar, Fatemeh Golshahi, Nafiseh Saedi, Fatemeh Rahimi Sharbaf, Mahboobeh Shirazi, Nooshin Faraji, Mohadese Dashtkoohi and 2 more

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In one paragraph

Article in Journal of reproduction & infertility. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Behrokh SahebdelDepartment of Obstetrics and Gynecology, Fetal and Neonatal Research Center, Yas Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Reihaneh Mortazavi ArdestaniDepartment of Radiology, Tehran University of Medical Sciences, Tehran, Iran.
Setareh SoltaniClinical Research Development Center, Taleghani and Imam Ali Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Mohammad Hossein GolezarAdvanced Diagnostic and Interventional Radiology Research Center (ADIR), Medical Imaging Center, Tehran University of Medical Sciences, Tehran, Iran.
Fatemeh GolshahiDepartment of Obstetrics and Gynecology, Fetal and Neonatal Research Center, Yas Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Nafiseh SaediDepartment of Obstetrics and Gynecology, Fetal and Neonatal Research Center, Yas Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Fatemeh Rahimi SharbafDepartment of Obstetrics and Gynecology, Fetal and Neonatal Research Center, Yas Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Mahboobeh ShiraziDepartment of Obstetrics and Gynecology, Fetal and Neonatal Research Center, Yas Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Nooshin FarajiDepartment of Obstetrics and Gynecology, Fetal and Neonatal Research Center, Yas Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Mohadese DashtkoohiVali-E-Asr Reproductive Health Research Center, Family Health Research Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Zohreh HeidaryVali-E-Asr Reproductive Health Research Center, Family Health Research Institute, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.
Masoumeh AslanpourDepartment of Obstetrics and Gynecology, Fetal and Neonatal Research Center, Yas Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cortical folding during fetal brain development reflects neural maturation. Fetal growth restriction (FGR) may disrupt this process, potentially affecting neurodevelopmental outcomes. Although ultrasound enables noninvasive sulcal assessment, so normative data and objective tools are lacking. The purpose of the current study was to assess the impact of FGR on fetal cortical development using neurosonography and establish a third-trimester nomogram for cortical maturation. Methods: This prospective study included 425 singleton pregnancies (330 appropriate-for-gestational-age [AGA], 54 symmetrical FGR, and 41 asymmetrical FGR) at 28-36 weeks. Conducted at a Tehran tertiary center (2023-2024), the study included cases with normal anatomy and negative aneuploidy screening. Neurosonographic parameters including Sylvian fissure (SF), insula, parieto-occipital fissure (POF), cavum septum pellucidum (CSP) width, and ventricular diameter were measured and the ratios calculated relative to biparietal diameter (BPD). ANOVA and post-hoc tests were applied and statistical significance was set at p<0.05. Results: No significant differences in neurosonographic ratios ( Conclusion: While absolute sulcal measurements vary with head size in FGR, biometric adjustments (

Indexed as

Cortical maturationFetal brain developmentFetal ultrasoundInsulaIntrauterine growth restrictionNeurosonographyNomogramSylvian fissure

Identifiers

PMID41586118
PMCPMC12828017

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.