ArticleFrontiers in neurology2025
Evaluation of the Wells score in predicting the incidence of stroke-associated pneumonia: the REMISE study.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Stroke-associated pneumonia (SAP) is a common complication in patients with stroke and is strongly associated with increased mortality and disability. Thrombotic burden may serve as a potential predictor of SAP. The Wells score, widely used to estimate the probability of thrombosis, offers a practical measure of thrombotic burden. This study aimed to investigate the utility of the Wells score in predicting the risk of SAP. Methods: A total of 755 adult patients diagnosed were retrospectively included. Patients were stratified based on the Wells score into three groups: low risk group (score 0), medium risk group (score 1-2), and high risk group (score ≥3). Multivariate logistic regression analysis was performed to examine the association between the Wells score and the incidence of SAP. Results: A total of 260 patients developed SAP during hospitalization. With the increasing Wells scores, the proportion of SAP showed a rising trend (the low vs. medium vs. high risk group: 16.8% vs. 39.0% vs. 58.4%, Conclusion: A high thrombotic burden is commonly observed in IS patients and is associated with an increased risk of SAP. Further research is needed to clarify the underlying mechanisms.
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