Evidence map›Paper›PMID 41586065›Full record

ArticleBrain, behavior, & immunity - health2026

Discrimination exposure and lymphocyte differentiation: Results from the health and retirement study.

Emiko O Kranz, Jemar R Bather, Xiaoyan Zhang, Virginia W Chang, Steven W Cole, Adolfo G Cuevas

Abstract read
In one paragraph

Article in Brain, behavior, & immunity - health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emiko O KranzDepartment of Social and Behavioral Sciences, NYU School of Global Public Health, New York, NY, USA.
Jemar R BatherDepartment of Biostatistics, NYU School of Global Public Health, New York, NY, USA.
Xiaoyan ZhangDepartment of Social and Behavioral Sciences, NYU School of Global Public Health, New York, NY, USA.
Virginia W ChangDepartment of Social and Behavioral Sciences, NYU School of Global Public Health, New York, NY, USA.
Steven W ColeDepartment of Psychiatry & Biobehavioral Sciences, UCLA, Los Angeles, CA, USA.
Adolfo G CuevasDepartment of Social and Behavioral Sciences, NYU School of Global Public Health, New York, NY, USA.

Funding

USC/UCLA Center on Biodemography &Population HealthP30AG017265 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JENNIFER A AILSHIRE · 1999 to 2026
$17.9M
NIA NIH HHS P30 AG017265
6 · The paper itself

Abstract

Everyday discrimination is a social determinant of health linked to disease and mortality, with one potential mechanism of this link involving stress-related signaling that "weathers" immune health. Previous research has examined links between discrimination and inflammatory processes derived from innate immune cells, but little is known about the associations of everyday discrimination with lymphoid lineage cells (T cells and B cells) that mediate adaptive immunity. To better understand the potential immunological impact of everyday discrimination, we analyzed the relationship between Everyday Discrimination Scale scores and flow cytometry data from the Health and Retirement Study (n = 6337; mean age = 70 years, SD = 9 years; 58 % female; 71 % White). Primary analyses adjusted for sociodemographic factors and secondary analyses additionally controlled for health behaviors. Weighted results showed that higher levels of discrimination were significantly associated with higher total CD4

Indexed as

Biological dysregulationEveryday discriminationImmunosenescenceLymphocytesPsychosocial stressors

Identifiers

PMID41586065
PMCPMC12828536

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.