Evidence map›Paper›PMID 41586060›Full record

ReviewStroke (Hoboken, N.J.)2024

Middle Meningeal Artery Embolization for Chronic Subdural Hematoma: A Review of Established and Emerging Embolic Agents.

Thilan Tudor, Stephen Capone, Juan Vivanco-Suarez, Mohamed M Salem, Georgios S Sioutas, Daniel A Tonetti, Daniel M Heiferman, Peter Kan, Brian T Jankowitz, Jan-Karl Burkhardt and 1 more

Abstract readReview
In one paragraph

Review in Stroke (Hoboken, N.J.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Middle meningeal artery embolization with standalone or adjunctive coiling for treatment of chronic subdural hematoma: Systematic review and meta-analysis.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Pooled it
  2. Pooled it
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  6. Review
  7. Review
  8. Bevacizumab: The future of chronic subdural hematoma.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Review
  9. Early single-center experience with middle meningeal artery embolization using ZoomInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026
    Article
  10. Review
  11. Article
  12. Review
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  14. Middle meningeal artery embolization as a stand-alone treatment for primary and recurrent chronic subdural hematoma.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  15. Article
  16. Middle meningeal artery embolization with SwiftPAC coils for the treatment of chronic subdural hematomas.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025
    Article
  17. Article
  18. Neurointerventional Advances in 2024.Stroke (Hoboken, N.J.) · 2025
    Article
  19. Review
  20. N-butyl Cyanoacrylate Use in Various Neuroendovascular Diseases.Journal of neuroendovascular therapy · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Thilan TudorDepartment of Neurosurgery, Hospital of the University of Pennsylvania Penn Medicine Philadelphia PA.
Stephen CaponeDepartment of Neurology Virginia Tech Carilion Clinic Roanoke VA.
Juan Vivanco-SuarezDepartment of Neurosurgery, Hospital of the University of Pennsylvania Penn Medicine Philadelphia PA.
Mohamed M SalemDepartment of Neurosurgery, Hospital of the University of Pennsylvania Penn Medicine Philadelphia PA.
Georgios S SioutasDepartment of Neurosurgery, Hospital of the University of Pennsylvania Penn Medicine Philadelphia PA.
Daniel A TonettiDepartment of Neurosurgery Cooper Neurological Institute Camden NJ.
Daniel M HeifermanDepartment of Neurosurgery Edward-Elmhurst Health Naperville IL.
Peter KanDepartment of Neurosurgery University of Texas Medical Branch Galveston TX.
Brian T JankowitzDepartment of Neurosurgery, Hospital of the University of Pennsylvania Penn Medicine Philadelphia PA.
Jan-Karl BurkhardtDepartment of Neurosurgery, Hospital of the University of Pennsylvania Penn Medicine Philadelphia PA.
Visish M SrinivasanDepartment of Neurosurgery, Hospital of the University of Pennsylvania Penn Medicine Philadelphia PA.ORCID https://orcid.org/0000-0001-7673-6805

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Middle meningeal artery embolization is an increasingly common procedure involved in the treatment of chronic subdural hematoma (cSDH) that can be an adjuvant intervention or an alternative to traditional medical or surgical therapies. Our review aims to summarize the mechanism, properties, and available clinical data for current and investigative embolic agents used for the treatment of cSDH. Pubmed, Scopus, and clinicaltrials.gov were searched for relevant studies and ongoing trials that examine middle meningeal artery embolization for cSDH. Particle agents, liquid embolic agents, and coil embolization are the common classes of embolic materials used in clinical practice and in ongoing trials. These embolic agents are not only mechanical occlusive materials; they have unique properties that address the angiogenic and proinflammatory mechanisms that propagate and sustain cSDH. Particle agents, such as polyvinyl alcohol and Embosphere (tris-acryl gelatin microspheres) have been the most commonly used embolic agents given the long-term evidence base regarding efficacy and established safety record. Liquid embolic agents such as cyanoacrylate glues and copolymer agents such as Onyx, Squid, and PHIL are increasingly common in clinical settings due to improved visualization on imaging, durable embolization, and better control of distal embolization. Coil embolization is used in conjunction with other embolic agents or as monotherapy in the setting of dangerous middle meningeal artery anastomoses. There are several ongoing randomized clinical trials and prospective cohort studies that will clarify the safety, efficacy, and use cases of particle agents, liquid embolic agents, and coil embolization for the treatment of cSDH.

Indexed as

chronic subdural hematomaclinical trialsembolic agentsembolizationendovascularmiddle meningeal artery

Identifiers

PMID41586060
PMCPMC12778451

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.