Evidence map›Paper›PMID 41586030›Full record

ArticleIJID regions2026

Update on the HDV seroprevalence and genotype distribution among patients positive for HBsAg referred to a National Reference Laboratory in Cameroon between January 2019 and December 2020.

Jacques Delors Toumansie Mfonkou, Yacouba Foupouapouognigni, Athenais Gerber, Ségolène Brichler, Frédéric Legal, Abdou Fatawou Modiyinji, Frederic Lissock, Laure Ngono, Boyomo Onana, Emmanuel Gordien and 1 more

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Article in IJID regions, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jacques Delors Toumansie MfonkouCentre Pasteur of Cameroon, Yaounde, Cameroon.
Yacouba FoupouapouognigniLaboratory of Pharmacology and Toxicology, University of Yaounde I, Yaounde, Cameroon.
Athenais GerberCentre National de Référence des Hépatites B, C et Delta, Laboratoire de Microbiologie Clinique, Hôpital Avicenne, Assistance Publique Hôpitaux de Paris, Bobigny, France.
Ségolène BrichlerCentre National de Référence des Hépatites B, C et Delta, Laboratoire de Microbiologie Clinique, Hôpital Avicenne, Assistance Publique Hôpitaux de Paris, Bobigny, France.
Frédéric LegalCentre National de Référence des Hépatites B, C et Delta, Laboratoire de Microbiologie Clinique, Hôpital Avicenne, Assistance Publique Hôpitaux de Paris, Bobigny, France.
Abdou Fatawou ModiyinjiCentre Pasteur of Cameroon, Yaounde, Cameroon.
Frederic LissockCentre Pasteur of Cameroon, Yaounde, Cameroon.
Laure NgonoCentre Pasteur of Cameroon, Yaounde, Cameroon.
Boyomo OnanaLaboratory of Microbiology, University of Yaounde I, Yaounde, Cameroon.
Emmanuel GordienCentre National de Référence des Hépatites B, C et Delta, Laboratoire de Microbiologie Clinique, Hôpital Avicenne, Assistance Publique Hôpitaux de Paris, Bobigny, France.
Richard NjouomCentre Pasteur of Cameroon, Yaounde, Cameroon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Cameroon is known to be endemic for hepatitis B virus infection, but available data on hepatitis delta virus (HDV) prevalence and genetic diversity are limited, inconsistent, and outdated. This study aimed to assess the current HDV prevalence and determine the HDV genotype distribution among patients positive for hepatitis B surface antigen (HBsAg) in Cameroon. Methods: This cross-sectional study examined patients positive for HBsAg from Cameroon's 10 administrative regions. Anti-HDV antibodies and HDV viral load (VL) were tested using validated commercial enzyme-linked immunosorbent assay and HDV VL quantification assays. HDV genotypes were determined by the Sanger sequencing method, followed by phylogenetic analysis of the "HDV R0" genome region previously described. Results: Of the 859 patients positive for HBsAg tested, 142 (16.5%) tested positive for anti-HDV, and HDV RNA was detected in 110 (77.5%) of them. The southern region of Cameroon had the highest infection rate. Notably, an undetectable hepatitis B virus VL was significantly associated with HDV infection ( Conclusions: Cameroon remains an endemic country for HDV, exhibiting high prevalence, remarkable regional distribution, and wide genetic diversity.

Indexed as

CameroonGenetic diversityHBVHDVPrevalence

Identifiers

PMID41586030
PMCPMC12825065

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.