Evidence map›Paper›PMID 41586028›Full record

ReviewJournal of ophthalmology2026

Selective Laser Trabeculoplasty Compared to Medication for Open-Angle Glaucoma Patients: A Systematic Review and Meta-Analysis.

Samantha So, Teng Qing Wang, Amardeep Thind, Cindy M L Hutnik, Monali S Malvankar-Mehta

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Journal of ophthalmology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Samantha SoDepartment of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Ontario, Canada, uwo.ca.ORCID https://orcid.org/0000-0001-7976-8618
Teng Qing WangDepartment of Medicine, Michael G. Degroote School of Medicine, McMaster University, Hamilton, Ontario, Canada, mcmaster.ca.ORCID https://orcid.org/0000-0002-8902-6797
Amardeep ThindDepartment of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Ontario, Canada, uwo.ca.ORCID https://orcid.org/0000-0003-1438-9531
Cindy M L HutnikDepartment of Ophthalmology, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Ontario, Canada, uwo.ca.ORCID https://orcid.org/0000-0001-9084-292X
Monali S Malvankar-MehtaDepartment of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Ontario, Canada, uwo.ca.ORCID https://orcid.org/0000-0001-7875-7386

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: An alternative glaucoma treatment is selective laser trabeculoplasty (SLT) that can effectively reduce intraocular pressure (IOP) and decrease the burden of glaucoma management. With newly published randomized controlled trials (RCTs) comparing SLT and medication, an updated systematic review and meta-analysis was needed. Methods: A literature search of RCTs comparing SLT and medication in open-angle glaucoma patients was conducted until January 12, 2024 in CINAHL, Cochrane Library, EMBASE, MEDLINE, Web of Science, ClinicalTrials.gov, and Dissertations and Theses databases. Cochrane Risk of Bias 2 (ROB2) was used to assess the quality of the included RCTs. Results: The included 16 RCTs comprised 2412 patients. At 26 weeks, the combination treatment of SLT and medication had a significant IOP reduction (SMD = 0.78, 95% CI = [0.56, 1.01], Conclusion: Long-term IOP reduction was greater in the SLT treatment compared to medication. SLT treatment significantly reduced the number of medications used by participants whereas medication group had no significant change.

Identifiers

PMID41586028
PMCPMC12828164

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.