Evidence map›Paper›PMID 41585916›Full record

ArticleStroke (Hoboken, N.J.)2023

Comparison of Drip-and-Ship Versus Mothership Delivery Models of Mechanical Thrombectomy Delivery.

Lucio D'Anna, Tsering Dolkar, Orsolya Vittay, Luke Dixon, Matteo Foschi, Michele Russo, Viva Levee, Paul Bentley, Zoe Brown, Charles Hall and 15 more

Abstract read
In one paragraph

Article in Stroke (Hoboken, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Observational
  5. Article
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  8. Article
  9. Observational
  10. Impact of atrial fibrillation on outcomes in stroke patients with tandem occlusions treated with thrombectomy: A multicentre study.International journal of stroke : official journal of the International Stroke Society · 2025
    Article
  11. Article
  12. Observational
  13. Article
  14. Observational
  15. "Chopperlysis": The effect of helicopter transport on reperfusion and outcomes in large vessel occlusion strokes.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2024
    Article
  16. Article
  17. Observational
  18. Article
  19. Observational
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Lucio D'AnnaDepartment of Stroke and Neuroscience Charing Cross Hospital Imperial College London NHS Healthcare Trust London UK.ORCID https://orcid.org/0000-0002-4349-3322
Tsering DolkarDepartment of Stroke and Neuroscience Charing Cross Hospital Imperial College London NHS Healthcare Trust London UK.
Orsolya VittayDepartment of Stroke and Neuroscience Charing Cross Hospital Imperial College London NHS Healthcare Trust London UK.
Luke DixonNeuroradiology Department of Imaging Charing Cross Hospital Imperial College London NHS Healthcare Trust London UK.
Matteo FoschiDepartment of Applied Clinical Sciences and Biotechnology University of L'Aquila L'Aquila Italy.
Michele RussoDepartment of Cardiology S. Maria dei Battuti Hospital Conegliano (TV) Italy.
Viva LeveeDepartment of Stroke and Neuroscience Charing Cross Hospital Imperial College London NHS Healthcare Trust London UK.
Paul BentleyDepartment of Stroke and Neuroscience Charing Cross Hospital Imperial College London NHS Healthcare Trust London UK.
Zoe BrownDepartment of Stroke and Neuroscience Charing Cross Hospital Imperial College London NHS Healthcare Trust London UK.
Charles HallNeuroradiology Department of Imaging Charing Cross Hospital Imperial College London NHS Healthcare Trust London UK.
Omid HalseDepartment of Stroke and Neuroscience Charing Cross Hospital Imperial College London NHS Healthcare Trust London UK.
Sohaa JamilDepartment of Stroke and Neuroscience Charing Cross Hospital Imperial College London NHS Healthcare Trust London UK.
Harri JenkinsDepartment of Stroke and Neuroscience Charing Cross Hospital Imperial College London NHS Healthcare Trust London UK.
Dheeraj KalladkaDepartment of Stroke and Neuroscience Charing Cross Hospital Imperial College London NHS Healthcare Trust London UK.
Joseph KwanDepartment of Stroke and Neuroscience Charing Cross Hospital Imperial College London NHS Healthcare Trust London UK.
Abid MalikDepartment of Stroke and Neuroscience Charing Cross Hospital Imperial College London NHS Healthcare Trust London UK.
Maneesh PatelNeuroradiology Department of Imaging Charing Cross Hospital Imperial College London NHS Healthcare Trust London UK.
Neil RaneNeuroradiology Department of Imaging Charing Cross Hospital Imperial College London NHS Healthcare Trust London UK.
Dylan RoiNeuroradiology Department of Imaging Charing Cross Hospital Imperial College London NHS Healthcare Trust London UK.
Abhinav SinghNeuroradiology Department of Imaging Charing Cross Hospital Imperial College London NHS Healthcare Trust London UK.
Marius VenterDepartment of Stroke and Neuroscience Charing Cross Hospital Imperial College London NHS Healthcare Trust London UK.
Eleanor TaylorNeuroradiology Department of Imaging Charing Cross Hospital Imperial College London NHS Healthcare Trust London UK.
Kyriakos LobotesisNeuroradiology Department of Imaging Charing Cross Hospital Imperial College London NHS Healthcare Trust London UK.
Soma BanerjeeDepartment of Stroke and Neuroscience Charing Cross Hospital Imperial College London NHS Healthcare Trust London UK.
Imperial Stroke Thrombectomy Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: It remains uncertain whether the drip-and-ship (DS) strategy (transport to the nearest primary stroke centers) or the mothership (MS) model (direct transportation to the comprehensive stroke center) is the organizational stroke model associated with the best functional outcome in acute stroke patients with large vessel occlusion. In this study, we compared the periprocedural complications and outcomes at 90 days of acute stroke patients with large vessel occlusion of the anterior circulation directly admitted to our comprehensive stroke center compared to those referred from primary stroke centers treated with mechanical thrombectomy. Methods: This is a single-center prospective observational study where patients with DS and MS were compared regarding the disability at 90 days, as assessed by applying the modified Rankin scale, the rate of successful reperfusion, and the rate of immediate complications postprocedure. Results: Of 579 patients, 216 (37.30%) were MS, and 363 (62.7%) were DS. There was no difference regarding the modified Rankin scale at 3 months between the MS (36.4%) and DS (39.3%) groups of patients treated with mechanical thrombectomy ( Conclusion: Our single-center study showed no difference in terms of functional independence between the DS and MS organizational paradigm. DS was associated with an increased risk of hemorrhagic transformation and symptomatic intracranial hemorrhage.

Indexed as

drip‐and‐shipischemic strokelarge vessel occlusionmechanical thrombectomymothership

Identifiers

PMID41585916
PMCPMC12778622

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.