Evidence map›Paper›PMID 41585765›Full record

ArticleStroke (Hoboken, N.J.)2023

Late Window Imaging Selection for Endovascular Therapy of Large Vessel Occlusion Stroke: An International Survey.

Thanh N Nguyen, Piers Klein, Anne Berberich, Simon Nagel, Mohamad Abdalkader, Ana Herning, Yimin Chen, Xiaochuan Huo, Zhongrong Miao, Sunil A Sheth and 56 more

Abstract read
In one paragraph

Article in Stroke (Hoboken, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  8. Hypoperfusion intensity ratio is associated with follow-up infarct volume in medium vessel occlusions: A multicenter multinational study.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Article
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  12. Endovascular Treatment for Basilar Artery Occlusion.Journal of clinical medicine · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

66 authors.

Thanh N NguyenDepartment of Neurology Boston Medical Center Boston MA.ORCID https://orcid.org/0000-0002-2810-1685
Piers KleinDepartment of Radiology Boston Medical Center Boston University Chobanian and Avedisian School of Medicine Boston MA.
Anne BerberichDepartment of Neurology Heidelberg University Hospital Heidelberg Germany.
Simon NagelDepartment of Neurology Heidelberg University Hospital Heidelberg Germany.
Mohamad AbdalkaderDepartment of Radiology Boston Medical Center Boston University Chobanian and Avedisian School of Medicine Boston MA.
Ana HerningDepartment of Neurology Boston Medical Center Boston MA.
Yimin ChenDepartment of Neurology Foshan Sanshui District People's Hospital China.
Xiaochuan HuoInterventional Neuroradiology Beijing Tiantan Hospital Beijing China.
Zhongrong MiaoInterventional Neuroradiology Beijing Tiantan Hospital Beijing China.
Sunil A ShethNeurology UTHealth McGovern Medical School Houston TX.
Muhammad M QureshiDepartment of Radiology Boston Medical Center Boston University Chobanian and Avedisian School of Medicine Boston MA.
James E SieglerCooper Neurological Institute Cooper University Hospital Camden NJ.
Simona SaccoNeuroscience Section Department of Biotechnological and Applied Clinical Sciences University of L'Aquila L'Aquila Italy.
Daniel StrbianDepartment of Neurology Helsinki University Hospital Helsinki Finland.
Urs FischerDepartment of Neurology Bern University Hospital University of Bern Department of Neurology Basel University Hospital University of Basel Switzerland.
Hiroshi YamagamiDepartment of Stroke Neurology National Hospital Organization Osaka National Hospital Osaka Japan.
Espen Saxhaug KristoffersenDepartment of Neurology Akershus University Hospital Lørenskog Department of General Practice University of Oslo Oslo Norway.
Volker PuetzDepartment of Neurology University Hospital Carl Gustav Carus Technische Universität Dresden Dresden Germany.
Wouter SchonewilleDepartment of Neurology St. Antonius Hospital Nieuwegein The Netherlands.
Georgios Tsivgoulis"Attikon" University Hospital National and Kapodistrian University of Athens Athens Greece.
Brian DrummDepartment of Stroke Medicine Imperial College Healthcare NHS Trust Charing Cross Hospital London UK.
Soma BanerjeeDepartment of Stroke Medicine Imperial College Healthcare NHS Trust Charing Cross Hospital London UK.
Jelle DemeestereNeurology Department Leuven University Hospital Leuven Belgium.
Fana AlemsegedDepartment of Medicine and Neurology Melbourne Brain Centre at the Royal Melbourne Hospital University of Melbourne Parkville Victoria Australia.
Else C SandsetDepartment of Neurology Oslo Norway and The Norwegian Air Ambulance Foundation Oslo Norway.
Anita Ante ArsovskaDepartment of Urgent Neurology University Clinic of Neurology University Ss. Cyril and Methodius-Faculty of Medicine Skopje North Macedonia.
Kailash KrishnanStroke Department of Medicine Nottingham University Hospitals NHS Trust Nottingham UK.
Permesh S DhillonInterventional Neuroradiology Nottingham University Hospitals NHS Trust Nottingham UK.
Angel CorredorDepartment of Neurology Hospital Departamental Universitario del Quindío San Juan de Dios Colombia.
Rodrigo RiveraNeuroradiology Department Instituto de Neurocirugía Dr. Asenjo Santiago Chile.
Petra SedovaDepartment of Neurology International Clinical Research Center, St Anne's University Hospital and Faculty of Medicine Masaryk University Brno Czech Republic.
Robert MikulikDepartment of Neurology International Clinical Research Center, St Anne's University Hospital and Faculty of Medicine Masaryk University Brno Czech Republic.
Hesham E MasoudDepartment of Neurology SUNY Upstate, Syracuse NY.
Sheila O MartinsNeurology Federal University of Rio Grande do Sul Porto Alegre Hospital de Clínicas de Porto Alegre Brazil.
Thang Huy NguyenCerebrovascular Disease Department 115 People Hospital Ho Chi Minh City Vietnam.
Mai Duy TonStroke Center Bach Mai Hospital Hanoi Medical University Hanoi Vietnam.
Xinfeng LiuStroke Center and Department of Neurology The First Affiliated Hospital of USTC Division of Life Sciences and Medicine University of Science and Technology of China Hefei China.
Yuyou ZhuStroke Center and Department of Neurology The First Affiliated Hospital of the University of Science and Technology of China Division of Life Sciences and Medicine University of Science and Technology of China Hefei Anhui China.
Fengli LiNeurology Xinqiao Hospital and The Second Affiliated Hospital Army Medical University Chongqing China.
Wan Asyraf Wan ZaidiDepartment of Medicine National University of Malaysia Malaysia.
Marialuisa ZeddeNeurology Unit Stroke Unit Azienda Unità Sanitaria Locale-IRCCS di Reggio Emilia Reggio Emilia Italy.
Shadi YaghiNeurology Rhode Island Hospital Brown University School of Medicine Providence RI.
Jian MiaoDepartment of Neurology Xianyang Hospital of Yan'an University Xianyang China.
Violiza InoaNeurology University of Tennessee Health Science Center TN.
Liqun ZhangSt George's University Hospital London UK.
Rytis MasiliūnasCenter of Neurology Vilnius University Vilnius Lithuania.
Peter SladeDepartment of Neurology International Clinical Research Center, St Anne's University Hospital and Faculty of Medicine Masaryk University Brno Czech Republic.
Sarah Shali MatujaDepartment of Internal Medicine Catholic University of Health and Allied Sciences Mwanza Tanzania.
João Pedro MartoDepartment of Neurology Hospital de Egas Moniz Centro Hospitalar Lisboa Ocidental Lisbon Portugal.
Patrik MichelNeurology Service Department of Clinical Neurosciences Lausanne University Hospital and University of Lausanne Lausanne Switzerland.
Jens FiehlerInterventionelle Neuroradiologie Hamburg Germany.
Götz ThomallaUniversitätsklinikum Hamburg-Eppendorf Klinik und Poliklinik für Neurologie Hamburg Germany.
Alicia C CastonguayDepartment of Neurology University of Toledo Toledo OH.
Maxim MokinNeurology University of South Florida Tampa FL.
Mark ParsonsDepartment of Neurology Liverpool Hospital New South Wales Australia.
Bruce C V CampbellDepartment of Medicine and Neurology Melbourne Brain Centre at the Royal Melbourne Hospital University of Melbourne Parkville Victoria Australia.
Dileep R YavagalNeurology and Neurosurgery University of Miami Miller School of Medicine FL.
Diederik DippelNeurology Erasmus MC University Medical Center Rotterdam Netherlands.
Mayank GoyalDepartment of Radiology University of Calgary Canada.
Osama O ZaidatNeuroscience and Stroke Program Bon Secours Mercy Health St Vincent Hospital Toledo OH.
Tudor G JovinCooper Neurological Institute Cooper University Hospital Camden NJ.
Wei HuStroke Center and Department of Neurology The First Affiliated Hospital of the University of Science and Technology of China Division of Life Sciences and Medicine University of Science and Technology of China Hefei Anhui China.
Raul G NogueiraDepartment of Neurology University of Pittsburgh Medical Center PA.
Zhongming QiuNeurology Xinqiao Hospital and The Second Affiliated Hospital Army Medical University Chongqing China.
Jean RaymondDepartment of Radiology Interventional Neuroradiology division Centre Hospitalier de l'Universite de Montreal.
Gustavo SaposnikStroke Outcomes and Decision Neuroscience Research Unit Division of Neurology University of Toronto Toronto Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Current stroke guidelines recommend advanced imaging (computed tomography [CT] perfusion or magnetic resonance imaging) prior to endovascular therapy (EVT) in patients with late presentation of large vessel occlusion. Adherence to guidelines may be constrained by resources or timely access to imaging. We sought to understand the factors which influence late window imaging selection for EVT candidates with large vessel occlusion. Methods: We conducted an international survey from January to May 2022. The questions aimed to identify advanced imaging and treatment decisions based on access to imaging, time delays, and simulated patient scenarios. Results: There were 3000 invited participants and 1506 respondents, the majority (89.6%) from comprehensive stroke centers in high-income countries. Neurointerventionalists comprised 31.8% and noninterventionalists 68.2% of respondents. Overall, 70.7% reported routine use of advanced imaging for late EVT selection, and 63.6% reported its usage in every case. There was greater availability of advanced imaging in comprehensive stroke centers versus primary stroke centers (67.0% versus 33.7%; Conclusion: Current guidelines for imaging late window EVT candidates are inconsistent with imaging decisions by physicians. Most respondents consider an imaging delay of greater than 20 minutes unacceptable. Access to advanced imaging was greater in comprehensive stroke centers and high-income countries. In the case of limited access most respondents would consider EVT based on CT only.

Indexed as

endovascular therapylarge vessel occlusionlate windowmechanical thrombectomy

Identifiers

PMID41585765
PMCPMC12778602

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.