Evidence map›Paper›PMID 41585745›Full record

ArticleStroke (Hoboken, N.J.)2023

Hybrid-Mobile Stroke Unit: Opening the Indication Spectrum for Stroke Mimics and Beyond.

Klaus Fassbender, Daniel J Phillips, Iris Q Grunwald, Andrea Schottek, Sajid Alam, Saman Perera, Annie Chakrabarti, Robert Moon, Martin Lesmeister, Viola Wagner and 12 more

Abstract read
In one paragraph

Article in Stroke (Hoboken, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Prehospital stroke management and mobile stroke units.Current opinion in neurology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Klaus FassbenderDepartment of Neurology Saarland University Medical Center Homburg Germany.
Daniel J PhillipsEast of England Ambulance Service NHS Trust Melbourn UK.
Iris Q GrunwaldImaging Science and Technology School of Medicine University of Dundee Dundee UK.
Andrea SchottekDepartment of Neurology Saarland University Medical Center Homburg Germany.
Sajid AlamEast Suffolk and North Essex NHS Foundation Trust Ipswich UK.
Saman PereraMid and South Essex NHS Foundation Trust Southend-on-Sea UK.
Annie ChakrabartiNorfolk and Norwich University Hospital NHS Foundation Trust Norwich UK.
Robert MoonEast of England Ambulance Service NHS Trust Melbourn UK.
Martin LesmeisterDepartment of Neurology Saarland University Medical Center Homburg Germany.
Viola WagnerDepartment of Neurology Saarland University Medical Center Homburg Germany.
Damon WheddonEast of England Ambulance Service NHS Trust Melbourn UK.
David DommettMid and South Essex NHS Foundation Trust Southend-on-Sea UK.
Brittany WellsEast of England Ambulance Service NHS Trust Melbourn UK.
Rheanne MiddletonEast of England Ambulance Service NHS Trust Melbourn UK.
Robert WillisEast of England Ambulance Service NHS Trust Melbourn UK.
Monika BachhuberDepartment of Neurology Saarland University Medical Center Homburg Germany.
Fatma MerzouDepartment of Neurology Saarland University Medical Center Homburg Germany.
Stefan WagenpfeilInstitute for Medical Biometry Epidemiology and Medical Informatics Saarland University Campus Homburg Saarland Germany.
Jineesh ThottathMid and South Essex NHS Foundation Trust Southend-on-Sea UK.
Thomas BertschInstitute of Clinical Chemistry Laboratory Medicine and Transfusion Medicine Nuremberg General Hospital Paracelsus Medical University Nuremberg Germany.
Silke WalterDepartment of Neurology Saarland University Medical Center Homburg Germany.
Hybrid‐MSU Working Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Despite proven benefits, the use of single-purpose mobile stroke units (MSUs) has raised concerns about their effective and cost-efficient integration into clinical practice, especially when considered for operation in nonurban areas. The MSU concept may benefit from opening the indication spectrum to include frequent stroke mimics and additional emergencies. Methods: The current observational study evaluated benefits for the treatment and triage decision-making of use of an MSU with extended capabilities (Hybrid-MSU), also including radiography, ultrasonography, extended point-of-care laboratory, ECG, electroencephalography, and advanced medications. Apart from patients with a dispatch code for "stroke", the ambulance was also dispatched to those with codes for "seizures", "falls with head trauma", "headache", "unconsciousness", "infection and pandemic", "chest pain", and "breathing problems". Results: For 250 patients treated by the Hybrid-MSU, but not for 250 conventionally treated patients, the prehospital diagnostic workup allowed, apart from treatment with stroke thrombolytics (n=15), prehospital administration of specific anticonvulsants (n=15), antibiotics (n=5), early secondary stroke prophylaxis with aspirin (n=49), and the Sepsis Six bundle (n=2). Prehospital diagnosis avoided 215 (86.0%) admissions to the emergency department, either by management at home (n=116, 46.4%) or by directly transferring patients to the required specialized wards (n=99, 39.6%). Conclusion: The current study demonstrates the feasibility of the use of a Hybrid-MSU and indicates its potential benefits for prehospital treatment and triage decision-making. Opening the indication spectrum, together with an act-alone ability, could be a key in the future integration of MSUs into routine health care.

Indexed as

mobile stroke unitprehospitalstroke

Identifiers

PMID41585745
PMCPMC12778600

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.