SynthesisPain research & management2026
Pain in People With Fibromyalgia Syndrome (FMS) Undergoing or Following Surgery: A Systematic Narrative Review.
Synthesis in Pain research & management, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Pain in People With Fibromyalgia Syndrome (FMS) Undergoing or Following Surgery: A Systematic Narrative Review.Pain research & management · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Fibromyalgia syndrome (FMS) is a chronic pain condition characterised by widespread pain, fatigue, sleep disturbance and cognitive problems. This systematic review aimed to characterise the perioperative experiences of FMS patients undergoing elective surgery, including pain, local anaesthetic (LA) efficacy, complications, and functional outcomes postoperatively. Methods: This systematic review was reported in accordance with the PRISMA guidelines. The protocol was registered on PROSPERO (CRD: 42022309297). MEDLINE, Embase and CENTRAL were searched from 1990 to 28 June 2024. Two reviewers independently undertook screening, data extraction and quality assessment. A narrative synthesis was conducted. Results: Nineteen relevant studies published between 1999 and 2024 were identified, mostly focussing on orthopaedic surgeries. Evidence suggests FMS patients may experience more acute postoperative pain at the surgical site and increased widespread spontaneous pain compared to non-FMS individuals. Opioid requirements may also be greater and is linked to the extent of symptomatology. Little data existed on the benefit of LA techniques. Large cohort studies found no overall increase in complications, but within FMS patients undergoing orthopaedic surgery, there were increased 30- and 90-day complications including anaemia, readmissions and pneumonia. Data indicate poorer early postoperative functional recovery in FMS patients. Interestingly, some studies reveal that treating perpetuating visceral pain sources may lead to improvements in spontaneous FMS pain and sensory thresholds beyond 3 months. Conclusions: The review highlights a paucity of evidence characterising the immediate perioperative course in FMS patients, indicating an important area for future research to optimise patient experiences and outcomes; however, individualised patient discussions are key.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.