Evidence map›Paper›PMID 41585552›Full record

ArticleFood chemistry: X2026

Exploring in vitro protein digestion of dry fermented sausage under different thermal processing methods: Peptidomics and molecular simulation.

Hui Wang, Changjin Yu, Zhen Wang, Lingshen Zhao, Xuehua Zhang, Mingming Zhu, Hanjun Ma

Abstract read
In one paragraph

Article in Food chemistry: X, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hui WangSchool of Food Science, Henan Institute of Science and Technology, Xinxiang 453003, China.
Changjin YuSchool of Food Science, Henan Institute of Science and Technology, Xinxiang 453003, China.
Zhen WangSchool of Food Science, Henan Institute of Science and Technology, Xinxiang 453003, China.
Lingshen ZhaoSchool of Food Science, Henan Institute of Science and Technology, Xinxiang 453003, China.
Xuehua ZhangSchool of Food Science, Henan Institute of Science and Technology, Xinxiang 453003, China.
Mingming ZhuSchool of Food Science, Henan Institute of Science and Technology, Xinxiang 453003, China.
Hanjun MaSchool of Food Science, Henan Institute of Science and Technology, Xinxiang 453003, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study investigated the effect of various thermal processing methods (steaming, boiling, roasting, and frying) on the protein digestibility of dry fermented sausages. The results showed that thermal processing improves gastric digestibility by inducing protein denaturation, transforming β-turns and α-helices into β-sheets. Among them, the steamed sausages exhibited the best protein digestion characteristics, with the highest combined gastric/intestinal digestibility (89.06%), the highest proportion of small peptides (<1000 Da) in the digestion products (39.29%), and abundant bioactive peptides with antithrombotic and antiamnesic effects. Molecular simulation results indicated that actin conformation at 90 °C is more open with increased flexibility, and its binding free energy with pepsin decreased from -61.32 kJ/mol to -66.75 kJ/mol, revealing the molecular mechanism of enhanced protein digestion from an energetic perspective. This study provides a theoretical basis for enhancing the nutritional quality of fermented meat products through optimized thermal processing.

Indexed as

DigestibilityDry fermented sausageIn vitro digestionMeat proteinMolecular simulations

Identifiers

PMID41585552
PMCPMC12825071

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.