Evidence map›Paper›PMID 41585332›Full record

ArticleIranian journal of otorhinolaryngology2026

Anti-inflammatory and Antioxidant Effects of Kaempferia galanga Extract in Acute Bacterial Rhinosinusitis: In Vivo Study on MDA, NF-κB, and CRP.

Aziza Viquisa Berliana Putri, Paramasari Dirgahayu, Bambangx Purwanto, Soetrisno Soetrisno, Betty Suryawati, Risya Cilmiaty, Hadi Sudrajad

Abstract read
In one paragraph

Article in Iranian journal of otorhinolaryngology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aziza Viquisa Berliana PutriDoctoral Program of Medical Science, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Surakarta, Indonesia.
Paramasari DirgahayuDoctoral Program of Medical Science, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Surakarta, Indonesia.
Bambangx PurwantoDoctoral Program of Medical Science, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Surakarta, Indonesia.
Soetrisno SoetrisnoDoctoral Program of Medical Science, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Surakarta, Indonesia.
Betty SuryawatiDoctoral Program of Medical Science, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Surakarta, Indonesia.
Risya CilmiatyDoctoral Program of Medical Science, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Surakarta, Indonesia.
Hadi SudrajadDepartement of Otorhinolaryngology, Faculty of Medicine, Universitas Sebelas Maret, Surakarta, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Acute bacterial rhinosinusitis (ABRS) is an inflammation of the paranasal sinuses caused by bacterial infection, primarily involving inflammatory responses and oxidative stress. While antibiotics are the standard treatment, their effectiveness can sometimes be limited. Materials and Methods: An in vivo experimental study was conducted using Sprague-Dawley rats with induced ABRS. The animals were randomly divided into three treatment groups that received Results: Eighteen rats with ABRS were included in the study. The KG300 group exhibited significantly lower levels of MDA, NF-κB, and CRP compared to the KG150 and KG450 groups (p < 0.05). These findings suggest that the 300 mg/kg dose of Conclusion:

Indexed as

Anti-inflammatory agentAntioxidantsKaempferia galangaOxidativeRhinosinusitis stress

Identifiers

PMID41585332
PMCPMC12828114

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.