Evidence map›Paper›PMID 41585283›Full record

ArticleStroke (Hoboken, N.J.)2022

Safety and Feasibility of Reconstructing Dissection Tandem Lesions with Flow Diverter Stents during Mechanical Thrombectomy for Acute Ischemic Stroke: A Multicenter Retrospective Case Series.

Humberto Diaz-Silva, Carlos Piñana, Laura Ludovica Gramegna, Manuel Requena, Eila Rivera, Eva María González, Juan José Fondevila Monsó, Oscar Chirife, Manuel Moreu, Pedro Vega and 8 more

Abstract read
In one paragraph

Article in Stroke (Hoboken, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Humberto Diaz-SilvaInterventional Neuroradiology Section, Department of Radiology Vall d'Hebron University Hospital, Vall d'Hebron Research Institute Barcelona Spain.
Carlos PiñanaInterventional Neuroradiology Section, Department of Radiology Vall d'Hebron University Hospital, Vall d'Hebron Research Institute Barcelona Spain.
Laura Ludovica GramegnaIRCCS Istituto Delle Scienze Neurologiche di Bologna Bologna Italy.
Manuel RequenaInterventional Neuroradiology Section, Department of Radiology Vall d'Hebron University Hospital, Vall d'Hebron Research Institute Barcelona Spain.
Eila RiveraInterventional Neuroradiology Section, Department of Radiology Vall d'Hebron University Hospital, Vall d'Hebron Research Institute Barcelona Spain.
Eva María GonzálezDepartament of Interventional Radiology-Neuroradiology Hospital Universitario de Cruces Bilbao Vizcaya Spain.
Juan José Fondevila MonsóDepartament of Interventional Radiology-Neuroradiology Hospital Universitario de Cruces Bilbao Vizcaya Spain.
Oscar ChirifeDepartment of Interventional Neuroradiology Hospital Universitari de Bellvitge Fundació Institut d'Investigació Biomèdica de Bellvitge L'Hospitalet de Llobregat Barcelona Spain.
Manuel MoreuNeurointerventional Unit Radiology Department Hospital Clínico Universitario San Carlos Madrid Spain.
Pedro VegaDepartment of Radiology-Interventional Neuroradiology Hospital Universitario Central de Asturias Oviedo Asturias Spain.
Sebastià RemolloNeurointerventional Radiology Unit Department of Neurosciences Hospital Germans Trias i Pujol Badalona Spain.
Mario MartínezNeuroradiology Unit Department of Radiology Hospital Clínico Universitario Valladolid Spain.
Jorge GalvánNeuroradiology Unit Department of Radiology Hospital Clínico Universitario Valladolid Spain.
Miguel SchullerNeuroradiology Unit Department of Radiology Hospital Clínico Universitario Valladolid Spain.
Luigi CirilloIRCCS Istituto Delle Scienze Neurologiche di Bologna Bologna Italy.
David HernándezInterventional Neuroradiology Section, Department of Radiology Vall d'Hebron University Hospital, Vall d'Hebron Research Institute Barcelona Spain.
Marc RiboThe Stroke Unit Department of Neurology Vall d'Hebron University Hospital Barcelona Spain.
Alejandro TomaselloInterventional Neuroradiology Section, Department of Radiology Vall d'Hebron University Hospital, Vall d'Hebron Research Institute Barcelona Spain.ORCID https://orcid.org/0000-0002-6736-1535

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients with acute ischemic stroke due to large vessel occlusion may present with concomitant carotid dissections that make the technical approach for their treatment challenging. The purpose of this study was to determine the safety and feasibility of flow diverter (FD) stents to treat carotid artery dissections in tandem lesions of acute ischemic stroke patients during mechanical thrombectomy. Methods: A retrospective review of all patients in which a carotid artery dissection was treated with an FD during endovascular treatment of acute ischemic stroke between 2018 and 2020 was conducted in 5 high-volume Comprehensive Stroke Centers. Patient clinical and angiographical characteristics, postoperative outcome, and follow-up were recorded. Results: A total of 12 patients (mean age: 54.18±14.74 years, median Alberta Stroke Program Early CT Score: 10 [interquartile range 9-10]) were included. Successful FD stenting with immediate patency of the dissected segments and successful intracranial recanalization modified thrombolysis in cerebral infarction score 2b-3 after thrombectomy was achieved in all patients. A good outcome (modified Rankin scale 0-2 at 90 days) was achieved in 66% (8/12) of patients. In 25% (3/12) of patients, an additional self-expanding carotid stent was used to anchor the FD proximally at the carotid bulb level. Complications included 1 symptomatic intracranial hemorrhage after procedure (24-48 hours) and 2 in-stent stenoses at follow-up. Conclusions: In this small case series, the treatment of carotid artery dissection with FD stents was safe and technically feasible during mechanical thrombectomy of acute ischemic stroke patients with tandem lesions and resulted in a high rate of good clinical outcome. These results may provide the basis for designing larger prospective studies to assess the efficacy and safety of FD stents in selected patients with carotid tandem lesions.

Indexed as

brain ischemiacarotid arterycarotid artery dissectionischemic strokestentsthrombectomy

Identifiers

PMID41585283
PMCPMC12778746

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.