Evidence map›Paper›PMID 41585184›Full record

ArticleJournal of dental sciences2026

Characterization of the oral microbiota in zygomatic versus dental implants: Implications for full-mouth rehabilitation.

Min-Yi Sung, Po-Chih Hsu, Chan-Yen Kuo, Liang-Kun Chen, Chung-Che Tsai, Yi-Chiung Hsu

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Article in Journal of dental sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Min-Yi SungDepartment of Biomedical Sciences and Engineering, National Central University, Taoyuan, Taiwan.
Po-Chih HsuDepartment of Dentistry, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan.
Chan-Yen KuoInstitute of Oral Medicine and Materials, College of Medicine, Tzu Chi University, Hualien, Taiwan.
Liang-Kun ChenDepartment of Biomedical Sciences and Engineering, National Central University, Taoyuan, Taiwan.
Chung-Che TsaiDepartment of Research, Taipei Tzu Chi Hospital, The Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan.
Yi-Chiung HsuDepartment of Biomedical Sciences and Engineering, National Central University, Taoyuan, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/purpose: Dental implants are widely used to restore oral function and esthetics in patients with tooth loss. General zygomatic implants (GZIs) are a valuable alternative for patients with severely atrophic maxillae or post-oncologic defects. However, implant placement can alter the ecological balance of the oral microbiota, potentially influencing peri-implant and sinus-related diseases. Because GZIs often traverse or adjoin the maxillary sinus, their microbial environment may differ from that of general dental implants (GDIs). This study aimed to compare microbiota taxonomy between GZI and GDI sites. Materials and methods: Generally healthy adults treated with either general zygomatic implants (GZI group) or general dental implants (GDI group) at a teaching hospital dental clinic were recruited. Biofilm samples were collected from implant surfaces under aseptic conditions. Microbial DNA was extracted and analyzed using 16S rRNA gene amplicon sequencing. Taxonomic classification and diversity analyses were performed through bioinformatic pipelines to identify bacterial genera and compare microbial community composition between groups. Results: Distinct microbial profiles were observed between the GZI and GDI groups. Rothia, Thermus, and Sphingomonas were significantly more abundant in the GZI group, whereas Capnocytophaga and Leptotrichia predominated in the GDI group, reflecting greater richness in the latter. Notably, Rothia species commonly linked to sinus infections were enriched in the GZI group, suggesting sinus-associated microbiome alterations. Conclusion: Implant type significantly influences peri-implant microbiota composition. Zygomatic implants exhibit distinct microbial communities potentially associated with sinus involvement. Further studies are needed to clarify their role in peri-implant and sinus-related pathogenesis.

Indexed as

16S rRNA sequencingDental implantMaxillary sinusOral microbiotaPeri-implant microbiomeZygomatic implant

Identifiers

PMID41585184
PMCPMC12826018

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