Evidence map›Paper›PMID 41585087›Full record

SynthesisFrontiers in neuroscience2025

Research hotspots and trends of amblyopia treatment from 2015 to 2025: a bibliometric analysis.

Chenyan Zhou, Xiaoru Li, Xiaoliang Luo, Shuning Song, Lvchun Wang, Junpeng Huang, Xiaobing Zhang, Die Liu, Yong Chai, Jiawei Zhou

Abstract readSystematic Review
In one paragraph

Synthesis in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chenyan ZhouState Key Laboratory of Eye Health, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Xiaoru LiState Key Laboratory of Eye Health, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Xiaoliang LuoChina Mobile Virtual Reality Innovation Center, Nanchang, China.
Shuning SongState Key Laboratory of Eye Health, Eye Hospital, Wenzhou Medical University, Wenzhou, China.
Lvchun WangChina Mobile Virtual Reality Innovation Center, Nanchang, China.
Junpeng HuangChina Mobile Virtual Reality Innovation Center, Nanchang, China.
Xiaobing ZhangChina Mobile Virtual Reality Innovation Center, Nanchang, China.
Die LiuChina Mobile Virtual Reality Innovation Center, Nanchang, China.
Yong ChaiDepartment of Ophthalmology, Jiangxi Provincial Children's Hospital, The Affiliated Children's Hospital of Nanchang Medical College, Nanchang, China.
Jiawei ZhouState Key Laboratory of Eye Health, Eye Hospital, Wenzhou Medical University, Wenzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This study aims to provide a comprehensive view of the current research status, hotspots, and emerging trends of amblyopia treatment through bibliometric analysis of published literature. Methods: We retrieved publications from the Web of Science Core Collection (WoSCC) and PubMed databases from 2015 to 2025. CiteSpace was used to analyze and visualize countries, institutions, journals, keywords, and references. Results: The analysis included 514 publications that show a steady increasing trend. The United States and China are the most productive countries. McGill University has made notable contributions to this field. The most prolific journal is the Journal of AAPOS, while high-impact journal JAMA Ophthalmology has the highest citations. Keyword and reference analyses reveal that the research focus has shifted to clinical trials and various binocular treatments. The analyses of the recent citation burst and clinical trials reflect the future trend of amblyopia treatment towards personalized and technologically optimized treatment and the validation of novel neuromodulation therapies. Conclusion: This study reveals the current hotspots and future directions of amblyopia treatment research. Current research focuses on clinical trials of binocular treatment through different digital platforms in amblyopia. Our findings provide critical insights for scientific and clinical research on amblyopia treatment.

Indexed as

amblyopiabibliometric analysisCiteSpacetherapytreatment

Identifiers

PMID41585087
PMCPMC12823900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.