ArticleStroke (Hoboken, N.J.)2023
Aspiration Versus Stent-Retriever as First-Line Endovascular Therapy Technique for Primary Medium and Distal Intracranial Occlusions: A Propensity-Score Matched Multicenter Analysis.
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Article in Stroke (Hoboken, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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23citing papers in PubMed, 1 pooled it
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Evidence, strategies, and pathways for thrombectomy in medium vessel occlusion stroke: a systematic review.Frontiers in neurology · 2026Pooled it
- Intra-Arterial Thrombolytic vs. Mechanical Thrombectomy in Distal Medium Middle Cerebral Artery Acute Ischemic Stroke: A Preliminary Multinational Multicenter Propensity Score-Matched Study.Clinical neuroradiology · 2026Observational
- Endovascular Thrombectomy in Medium and Distal Vessel Occlusions: A Focused Guideline From the Society of Vascular and Interventional Neurology Guidelines and Practice Standards Committee.Stroke (Hoboken, N.J.) · 2026Review
- Intravenous Thrombolysis in Distal Medium Middle Cerebral Artery Occlusion Patients with Unsuccessful Mechanical Reperfusion.Clinical neuroradiology · 2026Article
- Sex-Related Differences in Outcomes of Endovascular Treatment of Distal Medium Vessel Occlusion Strokes.Clinical neuroradiology · 2026Article
- Clinical outcomes of patients with unsuccessful mechanical thrombectomy versus best medical management of medium vessel occlusion stroke in the middle cerebral artery territory.Journal of neurointerventional surgery · 2025Article
- Hypoperfusion intensity ratio is associated with follow-up infarct volume in medium vessel occlusions: A multicenter multinational study.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Article
- Navigating severe vascular tortuosity and cervical carotid loop management in stroke thrombectomy: A case report and review of the literature.Journal of cerebrovascular and endovascular neurosurgery · 2025Article
- Efficacy and safety of mechanical thrombectomy in distal medium middle cerebral artery occlusion ischemic stroke patients on low-dose aspirin.International journal of stroke : official journal of the International Stroke Society · 2025Article
- Endovascular therapy versus medical management in isolated posterior cerebral artery acute ischemic stroke: A multinational multicenter propensity score-weighted study.European stroke journal · 2025Article
- Predictive value of follow-up infarct volume on functional outcomes in middle cerebral artery M2 segment vessel occlusion stroke treated with mechanical thrombectomy.European stroke journal · 2025Article
- Endovascular therapy versus medical management in isolated anterior cerebral artery acute ischemic stroke: a multinational multicenter propensity score-weighted study.Journal of neurointerventional surgery · 2025Article
- A multicenter, propensity score-matched analysis of functional outcomes and recanalization success with or without Trevo for Medium and distal vessel occlusion.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Association of Pretreatment Perfusion Imaging Parameters with 90-Day Excellent Functional Outcomes in Anterior Circulation Distal Medium Vessel Occlusion Stroke.AJNR. American journal of neuroradiology · 2025Article
- Outcomes of mechanical thrombectomy in anticoagulated patients with acute distal and medium vessel stroke.European stroke journal · 2024Article
- Predictors and Outcomes of Excellent Recanalization Versus Successful Recanalization After Thrombectomy in Proximal and Distal Medium Vessel Occlusion Strokes: A Multinational Study.Stroke (Hoboken, N.J.) · 2024Article
- Mechanical Thrombectomy Versus Intravenous Thrombolysis in Distal Medium Vessel Acute Ischemic Stroke: A Multinational Multicenter Propensity Score-Matched Study.Journal of stroke · 2024Article
- Assessment of Thrombectomy versus Combined Thrombolysis and Thrombectomy in Patients with Acute Ischemic Stroke and Medium Vessel Occlusion.Radiology · 2024Article
- CLEAR Thrombectomy Score: An Index to Estimate the Probability of Good Functional Outcome With or Without Endovascular Treatment in the Late Window for Anterior Circulation Occlusion.Journal of the American Heart Association · 2024Observational
- Prognostic value of recanalization attempts in endovascular therapy for M2 segment middle cerebral artery occlusions.International journal of stroke : official journal of the International Stroke Society · 2024Observational
Corrections and comments
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Authors and funding
93 authors.
James E SieglerCooper Neurological Institute Cooper University Hospital Camden New Jersey USA.
Hamza ShaikhCooper Neurological Institute Cooper University Hospital Camden New Jersey USA.
Jane KhalifeCooper Neurological Institute Cooper University Hospital Camden New Jersey USA.
Solomon OakCooper Medical School of Rowan University Camden New Jersey USA.
Linda ZhangCooper Medical School of Rowan University Camden New Jersey USA.
Mohamad AbdalkaderDepartments of Radiology & Neurology Boston Medical Center Boston Massachusetts USA.
Piers KleinDepartments of Radiology & Neurology Boston Medical Center Boston Massachusetts USA.
Thanh N NguyenDepartments of Radiology & Neurology Boston Medical Center Boston Massachusetts USA.
Tareq Kass-HoutDepartment of Neurology University of Chicago Chicago Illinois USA.
Rami Z MorsiDepartment of Neurology University of Chicago Chicago Illinois USA.
Jeremy J HeitDepartment of Interventional Neuroradiology Stanford Medical Center Palo Alto California USA.
Robert W RegenhardtNeuroendovascular Program Massachusetts General Hospital Harvard University Boston Massachusetts USA.
Jose Danilo Bengzon DiestroDivision of Diagnostic and Therapeutic Neuroradiology Department of Medical Imaging St. Michael's Hospital University of Toronto Toronto Canada.
Nicole M CancelliereDivision of Diagnostic and Therapeutic Neuroradiology Department of Medical Imaging St. Michael's Hospital University of Toronto Toronto Canada.
Sherief GhozyDepartment of Radiology Mayo Clinic Rochester Minnesota USA.
Ahmad SweidDepartments of Radiology & Neurology Boston Medical Center Boston Massachusetts USA.
Kareem El NaamaniDepartment of Neurosurgery Thomas Jefferson University Philadelphia Pennsylvania USA.
Abdelaziz AmllayDepartment of Neurosurgery Thomas Jefferson University Philadelphia Pennsylvania USA.
Lukas MeyerDepartment of Diagnostic and Interventional Neuroradiology University Medical Center Hamburg-Eppendorf Hamburg Germany.
Anne DusartDepartment of Neurology Hôpital Civil Marie Curie Charleroi Belgium.
Flavio BellanteDepartment of Neurology Hôpital Civil Marie Curie Charleroi Belgium.
Géraud ForestierUniversity Hospital of Limoges Neuroradiology Department Dupuytren Université de Limoges XLIM CNRS UMR 7252 Limoges France.
Aymeric RouchaudUniversity Hospital of Limoges Neuroradiology Department Dupuytren Université de Limoges XLIM CNRS UMR 7252 Limoges France.
Suzana SalemeUniversity Hospital of Limoges Neuroradiology Department Dupuytren Université de Limoges XLIM CNRS UMR 7252 Limoges France.
Charbel MounayerUniversity Hospital of Limoges Neuroradiology Department Dupuytren Université de Limoges XLIM CNRS UMR 7252 Limoges France.
Jens FiehlerDepartment of Diagnostic and Interventional Neuroradiology University Medical Center Hamburg-Eppendorf Hamburg Germany.
Anna Luisa KühnDivision of Neurointerventional Radiology Department of Radiology University of Massachusetts Medical Center Worcester Massachusetts USA.
Ajit S PuriDivision of Neurointerventional Radiology Department of Radiology University of Massachusetts Medical Center Worcester Massachusetts USA.
Christian DyzmannNeuroradiology Department Sana Kliniken Lübeck GmbH Lübeck Germany.
Peter T KanDepartment of Neurosurgery University of Texas Medical Branch Galveston Texas USA.
Marco ColasurdoDepartment of Neurosurgery University of Texas Medical Branch Galveston Texas USA.
Gaultier MarnatInterventional Neuroradiology Department Bordeaux University Hospital Bordeaux France.
Jérôme BergeInterventional Neuroradiology Department Bordeaux University Hospital Bordeaux France.
Xavier BarreauInterventional Neuroradiology Department Bordeaux University Hospital Bordeaux France.
Igor SibonNeurology Department Bordeaux University Hospital Bordeaux France.
Simona NedelcuDepartment of Neurology University of Massachusetts Chan Medical School Worcester Massachusetts USA.
Nils HenningerDepartment of Neurology University of Massachusetts Chan Medical School Worcester Massachusetts USA.
Thomas R MarottaDivision of Diagnostic and Therapeutic Neuroradiology Department of Medical Imaging St. Michael's Hospital University of Toronto Toronto Canada.
Alvin S DasDepartment of Neurology Beth Israel Deaconess Medical Center Harvard Medical School Boston Massachusetts USA.
Christopher J StapletonNeuroendovascular Program Massachusetts General Hospital Harvard University Boston Massachusetts USA.
James D RabinovNeuroendovascular Program Massachusetts General Hospital Harvard University Boston Massachusetts USA.
Takahiro OtaDepartment of Neurosurgery Tokyo Metropolitan Tama Medical Center Tokyo Japan.
Shogo DofukuDepartment of Neurosurgery Tokyo Metropolitan Tama Medical Center Tokyo Japan.
Leonard L L YeoDepartment of Medicine Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore.
Benjamin Y Q TanDepartment of Medicine Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore.
Juan Carlos Martinez-GutierrezDepartment of Neurology UTHealth McGovern Medical School Houston Texas USA.
Sergio Salazar-MarioniDepartment of Neurology UTHealth McGovern Medical School Houston Texas USA.
Sunil A ShethDepartment of Neurology UTHealth McGovern Medical School Houston Texas USA.
Leonardo RenieriInterventistica Neurovascolare Ospedale Careggi di Firenze Florence Italy.
Carolina CapirossiInterventistica Neurovascolare Ospedale Careggi di Firenze Florence Italy.
Ashkan MowlaDivision of Stroke and Endovascular Neurosurgery Department of Neurological Surgery Keck School of Medicine University of Southern California (USC) Los Angeles California USA.
Stavropoula I TjoumakarisDepartment of Neurosurgery Thomas Jefferson University Philadelphia Pennsylvania USA.
Pascal JabbourDepartment of Neurosurgery Thomas Jefferson University Philadelphia Pennsylvania USA.
Priyank KhandelwalDepartment of Endovascular Neurosurgery and Neuroradiology NJMS Newark New Jersey USA.
Arundhati BiswasDepartment of Neurosurgery Westchester Medical Center at New York Medical College Valhalla New York USA.
Frédéric ClarençonDepartment of Neuroradiology Pitié-Salpêtrière Hospital, GRC BioFast, Sorbonne University, Paris VI Paris France.
Mahmoud ElhoranyDepartment of Neuroradiology Pitié-Salpêtrière Hospital, GRC BioFast, Sorbonne University, Paris VI Paris France.
Kevin PrematDepartment of Neuroradiology Pitié-Salpêtrière Hospital, GRC BioFast, Sorbonne University, Paris VI Paris France.
Iacopo ValenteUOSA Neuroradiologia Interventistica Fondazione Policlinico Universitario A. Gemelli IRCCS Roma Florence Italy.
Alessandro PedicelliUOSA Neuroradiologia Interventistica Fondazione Policlinico Universitario A. Gemelli IRCCS Roma Florence Italy.
João Pedro FilipeDepartment of Diagnostic and Interventional Neuroradiology Centro Hospitalar Universitário do Porto Porto Portugal.
Ricardo VarelaDepartment of Neurology Centro Hospitalar Universitário do Porto Porto Portugal.
Miguel Quintero-ConsuegraDepartment of Neurosurgery Cedars-Sinai Medical Center Los Angeles California USA.
Nestor R GonzalezDepartment of Neurosurgery Cedars-Sinai Medical Center Los Angeles California USA.
Markus A MöhlenbruchSektion Vaskuläre und Interventionelle Neuroradiologie Universitätsklinikum Heidelberg Heidelberg Germany.
Jessica JesserSektion Vaskuläre und Interventionelle Neuroradiologie Universitätsklinikum Heidelberg Heidelberg Germany.
Vincent CostalatDepartment of Neuroradiology Gui de Chauliac Hospital Montpellier University Medical Center Montpellier France.
Adrien Ter SchiphorstDepartment of Neurology Gui de Chauliac Hospital Montpellier University Medical Center Montpellier France.
Vivek YedavalliDepartment of Radiology Division of Neuroradiology Johns Hopkins Medical Center Baltimore Maryland USA.
Pablo HarkerDepartment of Neurology University of Cincinnati Medical Center Cincinnati Ohio USA.
Lina M ChervakDepartment of Neurology University of Cincinnati Medical Center Cincinnati Ohio USA.
Yasmin AzizDepartment of Neurology University of Cincinnati Medical Center Cincinnati Ohio USA.
Maria Bres BullrichDepartments of Medical Imaging & Neurology LHSC University Hospital London Ontario Canada.
Luciano SposatoDepartments of Medical Imaging & Neurology LHSC University Hospital London Ontario Canada.
Benjamin GoryDepartment of Interventional Neuroradiology Nancy University Hospital Nancy France.
Constantin HeckerDepartments of Neurology & Neurosurgery Christian Doppler Clinic Paracelsus Medical University Salzburg Salzburg Austria.
Monika Killer-OberpfalzerDepartments of Neurology & Neurosurgery Christian Doppler Clinic Paracelsus Medical University Salzburg Salzburg Austria.
Christoph J GriessenauerDepartments of Neurology & Neurosurgery Christian Doppler Clinic Paracelsus Medical University Salzburg Salzburg Austria.
Ajith J ThomasCooper Neurological Institute Cooper University Hospital Camden New Jersey USA.
Cheng-Yang HsiehNeurology Department Sin-Lau Hospital Tainan Taiwan.
David S LiebeskindUCLA Stroke Center and Department of Neurology Department UCLA Los Angeles California USA.
Răzvan Alexandru RaduDepartment of Neuroradiology Gui de Chauliac Hospital Montpellier University Medical Center Montpellier France.
Andrea M AlexandreUOSA Neuroradiologia Interventistica Fondazione Policlinico Universitario A. Gemelli IRCCS Roma Florence Italy.
Illario TancrediDepartment of Diagnostic and Interventional Neuroradiology Erasme University Hospital Brussels Belgium.
Tobias D FaizyDepartment of Diagnostic and Interventional Neuroradiology University Medical Center Hamburg-Eppendorf Hamburg Germany.
Robert FahedDepartment of Medicine Division of Neurology The Ottawa Hospital Ottawa Hospital Research Institute and University of Ottawa Ottawa Ontario Canada.
Charlotte WeylandSektion Vaskuläre und Interventionelle Neuroradiologie Universitätsklinikum Heidelberg Heidelberg Germany.
Aman B PatelNeuroendovascular Program Massachusetts General Hospital Harvard University Boston Massachusetts USA.
Vitor Mendes PereiraDivision of Diagnostic and Therapeutic Neuroradiology Department of Medical Imaging St. Michael's Hospital University of Toronto Toronto Canada.
Boris LubiczDepartment of Diagnostic and Interventional Neuroradiology Erasme University Hospital Brussels Belgium.
Adrien GuenegoDepartment of Diagnostic and Interventional Neuroradiology Erasme University Hospital Brussels Belgium.
Adam A DmytriwNeuroendovascular Program Massachusetts General Hospital Harvard University Boston Massachusetts USA.ORCID https://orcid.org/0000-0003-0131-5699
MAD‐MT Consortium
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: For acute proximal intracranial artery occlusions, contact aspiration may be more effective than stent-retriever for first-line reperfusion therapy. Due to the lack of data regarding medium vessel occlusion thrombectomy, we evaluated outcomes according to first-line technique in a large, multicenter registry. Methods: Imaging, procedural, and clinical outcomes of patients with acute proximal medium vessel occlusions (M2, A1, or P1) or distal medium vessel occlusions (M3, A2, P2, or further) treated at 37 sites in 10 countries were analyzed according to first-line endovascular technique (stent-retriever versus aspiration). Multivariable logistic regression and propensity-score matching were used to estimate the odds of the primary outcome, expanded Thrombolysis in Cerebral Infarction score of 2b-3 ("successful recanalization"), as well as secondary outcomes (first-pass effect, expanded Thrombolysis in Cerebral Infarction 2c-3, intracerebral hemorrhage, and 90-day modified Rankin scale, 90-day mortality) between treatment groups. Results: Of the 440 included patients (44.5% stent-retriever versus 55.5% aspiration), those treated with stent-retriever had lower baseline Alberta Stroke Program Early Computed Tomography Scale scores (median 8 versus 9; Conclusion: In this large, diverse, multinational medium vessel occlusion cohort, we found no significant difference in imaging or clinical outcomes with aspiration versus stent-retriever thrombectomy.
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