Evidence map›Paper›PMID 41585051›Full record

ArticleStroke (Hoboken, N.J.)2023

Prehospital Triage of Intracranial Hemorrhage and Anterior Large-Vessel Occlusion Ischemic Stroke: Value of the Rapid Arterial Occlusion Evaluation.

Luuk Dekker, Victor J Geraedts, Jeroen Hubert, Dion Duijndam, Marcel D J Durieux, Loes Janssens, Wouter A Moojen, Erik W van Zwet, Marieke J H Wermer, Nyika D Kruyt and 1 more

Abstract read
In one paragraph

Article in Stroke (Hoboken, N.J.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Luuk DekkerDepartment of Neurology Leiden University Medical Center Leiden the Netherlands.ORCID https://orcid.org/0000-0002-0958-2081
Victor J GeraedtsDepartment of Neurology Leiden University Medical Center Leiden the Netherlands.
Jeroen HubertInstitute of Biology Leiden University Leiden the Netherlands.
Dion DuijndamEmergency Medical Services Haaglanden The Hague the Netherlands.
Marcel D J DurieuxEmergency Medical Services Hollands-Midden Leiden the Netherlands.
Loes JanssensEmergency Medical Services Haaglanden The Hague the Netherlands.
Wouter A MoojenDepartment of Neurosurgery Haaglanden Medical Center The Hague the Netherlands.
Erik W van ZwetDepartment of Biomedical Data Sciences Leiden University Medical Center Leiden the Netherlands.
Marieke J H WermerDepartment of Neurology Leiden University Medical Center Leiden the Netherlands.
Nyika D KruytDepartment of Neurology Leiden University Medical Center Leiden the Netherlands.
Ido R van den WijngaardDepartment of Neurology Leiden University Medical Center Leiden the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The Rapid Arterial oCclusion Evaluation (RACE) score can identify patients with anterior circulation large-vessel occlusion (aLVO) ischemic stroke for transportation to a comprehensive stroke center for endovascular thrombectomy. However, patients with intracranial hemorrhage (ICH) may also benefit from direct transportation to a comprehensive stroke center for neurosurgical treatment. We aimed to assess if the RACE score can distinguish patients with ICH in addition to aLVO stroke from other patients with suspected stroke. Methods: We analyzed data from the LPSS (Leiden Prehospital Stroke Study), a multicenter, prospective, observational cohort study in 2 Dutch ambulance regions. Ambulance paramedics documented prehospital observations in all patients aged ≥18 years with suspected stroke. We calculated the sensitivity, specificity, positive predictive value, and negative predictive value of a positive RACE score (≥5 points) for a diagnosis of ICH or aLVO stroke, compared with patients with non-aLVO stroke, transient ischemic attack, or stroke mimic. In addition, we performed a multivariable logistic regression analysis and calculated adjusted odds ratios (ORs). Results: We included 2004 patients with a stroke code, of whom 149 had an ICH, 153 had an aLVO stroke, 687 had a non-aLVO stroke, 262 had a transient ischemic attack, and 753 had a stroke mimic. Patients with ICH and aLVO stroke more often had a positive RACE score than other patients with suspected stroke (46.2% and 58.0%, respectively, versus 6.4%; Conclusions: Our study shows that the RACE score can also identify patients with ICH in addition to aLVO stroke. This emphasizes the potential of the RACE score for improving prehospital triage and allocation of patients with stroke.

Indexed as

endovascular thrombectomyhemorrhagic strokeintracerebral hemorrhageintracranial hemorrhagelarge‐vessel occlusionprehospital triagestroke

Identifiers

PMID41585051
PMCPMC12778717

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.